Analysis of gene-environment interactions related to developmental disorders

Y Nishimura, K Kurosawa - Frontiers in pharmacology, 2022 - frontiersin.org
Various genetic and environmental factors are associated with developmental disorders
(DDs). It has been suggested that interaction between genetic and environmental factors …

Bisphenol A-induced neurobehavioral transformation is associated with augmented monoamine oxidase activity and neurodegeneration in zebrafish brain

LK Pradhan, P Sarangi, PK Sahoo, S Kundu… - Environmental …, 2023 - Elsevier
As bisphenol A (BPA) effortlessly crosses the blood-brain barrier, its serious impacts on the
neuronal microenvironment towards precocious induction of oxidative stress and …

Development of the fish invitrome for animal-free environmental risk assessment of chemicals

M Revel, K Groh, J Bertoli, MO Degeratu… - Environmental …, 2025 - academic.oup.com
Given the need to reduce animal testing for environmental risk assessment, we aim to
develop a fish invitrome, an alternative fish modular framework capable of predicting …

[HTML][HTML] The Neurotoxic Effect of Environmental Temperature Variation in Adult Zebrafish (Danio rerio)

E Maffioli, S Nonnis, F Grassi Scalvini, A Negri… - International Journal of …, 2023 - mdpi.com
Neurotoxicity consists of the altered functionality of the nervous system caused by exposure
to chemical agents or altered chemical–physical parameters. The neurotoxic effect can be …

From causal networks to adverse outcome pathways: A developmental neurotoxicity case study

Ž Ramšak, V Modic, RA Li, C Vom Berg… - Frontiers in …, 2022 - frontiersin.org
The last decade has seen the adverse outcome pathways (AOP) framework become one of
the most powerful tools in chemical risk assessment, but the development of new AOPs …

Leveraging artificial intelligence to advance the understanding of chemical neurotoxicity

M Aschner, R Mesnage, AO Docea, MMB Paoliello… - Neurotoxicology, 2022 - Elsevier
Neurotoxicology is a specialty that aims to understand and explain the impact of chemicals,
xenobiotics and physical conditions on nervous system function throughout the life span …

RNA-seq reveals potential gene biomarkers in fathead minnows (Pimephales promelas) for exposure to treated wastewater effluent

PG Schumann, EB Meade, H Zhi… - … Science: Processes & …, 2022 - pubs.rsc.org
Discharged wastewater treatment plant (WWTP) effluent greatly contributes to the
generation of complex mixtures of contaminants of emerging concern (CECs) in aquatic …

Molecular and Behavioral Impacts of Treated Wastewater Effluent on Fish

P Schumann - 2022 - search.proquest.com
Currently, most studies that focus on the sublethal impacts of contaminants of emerging
concern (CECs) such as pharmaceuticals utilize a single-compound approach, whereas …

[PDF][PDF] Tk kkkk RNA-seq reveals potential gene biomarkers in fathead minnows (Pinnephales promelas) for

DW Kolpin, SM Meppelink, LR Iwanowicz, RF Lane… - researchgate.net
Wastewater treatment plants (WWTPs) greatly contribute to the formation of complex
mixtures of contaminants of emerging concern (CECs) in aquatic environments. The …