EMT: 2016

MA Nieto, RYJ Huang, RA Jackson, JP Thiery - cell, 2016 - cell.com
The significant parallels between cell plasticity during embryonic development and
carcinoma progression have helped us understand the importance of the epithelial …

Implications of the hybrid epithelial/mesenchymal phenotype in metastasis

MK Jolly, M Boareto, B Huang, D Jia, M Lu… - Frontiers in …, 2015 - frontiersin.org
Transitions between epithelial and mesenchymal phenotypes–the epithelial to
mesenchymal transition (EMT) and its reverse the mesenchymal to epithelial transition …

In primary airway epithelial cells, the unjamming transition is distinct from the epithelial-to-mesenchymal transition

JA Mitchel, A Das, MJ O'Sullivan, IT Stancil… - Nature …, 2020 - nature.com
The epithelial-to-mesenchymal transition (EMT) and the unjamming transition (UJT) each
comprises a gateway to cellular migration, plasticity and remodeling, but the extent to which …

EMT and MET: necessary or permissive for metastasis?

MK Jolly, KE Ware, S Gilja, JA Somarelli… - Molecular …, 2017 - Wiley Online Library
Epithelial‐to‐mesenchymal transition (EMT) and its reverse mesenchymal‐to‐epithelial
transition (MET) have been suggested to play crucial roles in metastatic dissemination of …

Tumor budding: the name is EMT. Partial EMT.

AD Grigore, MK Jolly, D Jia, MC Farach-Carson… - Journal of clinical …, 2016 - mdpi.com
Tumor budding is a histological phenomenon encountered in various cancers, whereby
individual malignant cells and/or small clusters of malignant cells are seen in the tumor …

TGF-β–induced epithelial-to-mesenchymal transition proceeds through stepwise activation of multiple feedback loops

J Zhang, XJ Tian, H Zhang, Y Teng, R Li, F Bai… - Science …, 2014 - science.org
The process of epithelial-to-mesenchymal transition (EMT) is an essential type of cellular
plasticity associated with a change from epithelial cells that function as a barrier consisting …

Cancer cell invasion and EMT marker expression: a three‐dimensional study of the human cancer–host interface

P Bronsert, K Enderle‐Ammour, M Bader… - The Journal of …, 2014 - Wiley Online Library
Cancer cell invasion takes place at the cancer–host interface and is a prerequisite for distant
metastasis. The relationships between current biological and clinical concepts such as cell …

Coupled reversible and irreversible bistable switches underlying TGFβ-induced epithelial to mesenchymal transition

XJ Tian, H Zhang, J **ng - Biophysical journal, 2013 - cell.com
Epithelial to mesenchymal transition (EMT) plays an important role in embryonic
development, tissue regeneration, and cancer metastasis. Whereas several feedback loops …

The plasticity of pancreatic cancer stem cells: Implications in therapeutic resistance

K Patil, FB Khan, S Akhtar, A Ahmad… - Cancer and Metastasis …, 2021 - Springer
The ever-growing perception of cancer stem cells (CSCs) as a plastic state rather than a
hardwired defined entity has evolved our understanding of the functional and biological …

Combinatorial interventions inhibit TGFβ-driven epithelial-to-mesenchymal transition and support hybrid cellular phenotypes

SN Steinway, JGT Zañudo, PJ Michel… - NPJ systems biology …, 2015 - nature.com
Epithelial-to-mesenchymal transition (EMT) is a developmental process hijacked by cancer
cells to leave the primary tumor site, invade surrounding tissue and establish distant …