Obesity and aging: Molecular mechanisms and therapeutic approaches

AL Santos, S Sinha - Ageing Research Reviews, 2021 - Elsevier
The epidemic of obesity is a major challenge for health policymakers due to its far-reaching
effects on population health and potentially overwhelming financial burden on healthcare …

Revisiting the adipocyte: a model for integration of cytokine signaling in the regulation of energy metabolism

A Rodríguez, S Ezquerro… - American Journal …, 2015 - journals.physiology.org
Adipose tissue constitutes an extremely active endocrine organ with a network of signaling
pathways enabling the organism to adapt to a wide range of different metabolic challenges …

Diet's role in modifying risk of Alzheimer's disease: history and present understanding

WB Grant, SM Blake - Journal of Alzheimer's Disease, 2023 - journals.sagepub.com
Diet is an important nonpharmacological risk-modifying factor for Alzheimer's disease (AD).
The approaches used here to assess diet's role in the risk of AD include multi-country …

Bioactive lipid mediators in skin inflammation and immunity

AC Kendall, A Nicolaou - Progress in lipid research, 2013 - Elsevier
The skin is the primary barrier from the outside environment, protecting the host from injury,
infectious pathogens, water loss and solar ultraviolet radiation. In this role, it is supported by …

Fatty acid binding proteins: tissue-specific functions in health and disease

AE Thumser, JB Moore, NJ Plant - Current Opinion in Clinical …, 2014 - journals.lww.com
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Obesity-associated cardiovascular risk in women: hypertension and heart failure

JL Faulkner - Clinical Science, 2021 - portlandpress.com
The pathogenesis of obesity-associated cardiovascular diseases begins long prior to the
presentation of a cardiovascular event. In both men and women, cardiovascular events, and …

Mechanisms linking excess adiposity and carcinogenesis promotion

AI Pérez-Hernández, V Catalán… - Frontiers in …, 2014 - frontiersin.org
Obesity constitutes one of the most important metabolic diseases being associated to insulin
resistance development and increased cardiovascular risk. Association between obesity …

Adipokines as a link between obesity and chronic kidney disease

JF Briffa, AJ McAinch, P Poronnik… - American Journal of …, 2013 - journals.physiology.org
Adipocytes secrete a number of bioactive adipokines that activate a variety of cell signaling
pathways in central and peripheral tissues. Obesity is associated with the altered production …

[HTML][HTML] Angiogenesis in obesity

P Nijhawans, T Behl, S Bhardwaj - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Purpose Angiogenesis is considered as a major progenitor in the progression of obesity.
The current manuscript enumerates the extrinsic role of angiogenesis in obesity. Result High …