Harnessing natural compounds to modulate miRNAs in breast cancer therapy
Breast cancer's complexity and heterogeneity continue to present significant challenges in
its treatment and management. Emerging research has underscored the pivotal role of …
its treatment and management. Emerging research has underscored the pivotal role of …
Unveiling the pharmacological potential of plant triterpenoids in breast cancer management: An updated review
Breast cancer is the most prevalent type of cancer, the fifth leading cause of cancer-related
deaths, and the second leading cause of cancer deaths among women globally. Recent …
deaths, and the second leading cause of cancer deaths among women globally. Recent …
Unveiling anti-diabetic potential of new thiazole-sulfonamide derivatives: Design, synthesis, in vitro bio-evaluation targeting DPP-4, α-glucosidase, and α-amylase with …
Diabetes mellitus type 2 (T2DM) can be managed by targeting dipeptidyl peptidase-4 (DPP-
4), an enzyme that breaks down and deactivates peptides such as GIP and GLP-1. In this …
4), an enzyme that breaks down and deactivates peptides such as GIP and GLP-1. In this …
Small Steps to the Big Picture for Health‐Promoting Applications Through the Use of Chickweed (Stellaria media): In Vitro, In Silico, and Pharmacological Network …
G Cusumano, GA Flores, MV Cetiz, U Kurt… - Food Science & …, 2024 - Wiley Online Library
Stellaria media L., also called chickweed, is widespread in all parts of the world. In the
present study, we investigated the biological properties and chemical profiles of different …
present study, we investigated the biological properties and chemical profiles of different …
Innovation of 6-sulfonamide-2 H-chromene derivatives as antidiabetic agents targeting α-amylase, α-glycosidase, and PPAR-γ inhibitors with in silico molecular …
A new series of 2-imino or 2-oxo-2H-chromene-6-sulfonamide derivatives 2–9 with potential
anti-diabetic activity were designed and synthesized. The new 6-sulfonamide chromenes …
anti-diabetic activity were designed and synthesized. The new 6-sulfonamide chromenes …
Discovery of novel 6-(piperidin-1-ylsulfonyl)-2H-chromenes targeting α-glucosidase, α-amylase, and PPAR-γ: Design, synthesis, virtual screening, and anti-diabetic …
A new series of 2H-chromene-based sulfonamide derivatives 3-12 has been synthesized
and characterized using different spectroscopic techniques. The synthesized 2H-chromenes …
and characterized using different spectroscopic techniques. The synthesized 2H-chromenes …
Discovery of new anti-diabetic potential agents based on paracetamol incorporating sulfa-drugs: Design, synthesis, α-amylase and α-glucosidase inhibitors with …
Uncontrolled diabetes can lead to hyperglycemia, which causes neuropathy, heart attacks,
retinopathy, and nervous system damage over time, therefore, controlling hyperglycemia …
retinopathy, and nervous system damage over time, therefore, controlling hyperglycemia …
Exploring the phytochemicals, antioxidant properties, and hepatoprotective potential of Moricandia sinaica leaves against paracetamol-induced toxicity: Biological …
Thirteen components were identified in the methanol extract of Moricandia sinaica leaves
(MSLE) through analysis utilizing HPLC-ESI-MS/MS., including flavonoids, anthocyanins …
(MSLE) through analysis utilizing HPLC-ESI-MS/MS., including flavonoids, anthocyanins …
Decoding chemical profiles and biological activities of aerial parts and roots of Eryngium thorifolium Boiss by HPLC-MS/MS, GC-MS and in vitro chemical assays
Eryngium species are widely distributed and primarily utilised for medicinal and culinary
purposes. This study aimed to evaluate the chemical composition, antioxidant, enzyme …
purposes. This study aimed to evaluate the chemical composition, antioxidant, enzyme …
Herbal remedies for oral and dental health: a comprehensive review of their multifaceted mechanisms including antimicrobial, anti-inflammatory, and antioxidant …
Across diverse cultures, herbal remedies have been used to alleviate oral discomfort and
maintain dental hygiene. This review presents studies on herbal remedies with remarkable …
maintain dental hygiene. This review presents studies on herbal remedies with remarkable …