Quantitative MRI provides biophysical measures of the microstructural integrity of the CNS,
which can be compared across CNS regions, patients, and centres. In patients with multiple …

Diffusion MRI is arguably the method of choice for characterizing white matter microstructure
in vivo. Over the typical duration of diffusion encoding, the displacement of water molecules …

The biophysical modeling efforts in diffusion MRI have grown considerably over the past 25
years. In this review, we dwell on the various challenges along the journey of bringing a …

Quantitative diffusion imaging techniques enable the characterization of tissue
microstructural properties of the human brain “in vivo”, and are widely used in neuroscientific …

To detect multiple sclerosis (MS) diseases early, we proposed a novel method on the
hardware of magnetic resonance imaging, and on the software of three successful methods …

Myelin is the protective sheath wrapped around axons, consisting of a phospholipid bilayer
with water between the wraps. The measurement of damage to the myelin sheaths, the …

Purpose The general utility of diffusion kurtosis imaging (DKI) is challenged by its poor
robustness to imaging artifacts and thermal noise that often lead to implausible kurtosis …

Objective To investigate the microstructural properties of T2 lesion and normal-appearing
white matter (NAWM) in 20 white matter tracts between multiple sclerosis (MS) and …

The recent introduction of advanced magnetic resonance (MR) imaging techniques to
characterize focal and global degeneration in multiple sclerosis (MS), like the Composite …

Diffusion tensor imaging (DTI) has been established its usefulness in evaluating normal-
appearing white matter (NAWM) and other lesions that are difficult to evaluate with routine …