METHODS: PubMed, Cochrane library, Scopus, Google Scholar, and Clinicaltrial. gov
databases were searched for literature published between September 2007 and December …

Background Irritable bowel syndrome is a functional gastrointestinal disease. Evidence has
suggested that probiotics may benefit IBS symptoms. However, clinical trials remain …

Psychiatric drugs have primacy for off-label prescribing. Among those, selective serotonin
reuptake inhibitors (SSRIs) are highly versatile and, therefore, widely prescribed. Moreover …

Results Certain conventional pain managing drugs do not effectively improve IBS symptoms,
including NSAIDs, acetaminophen, aspirin, and various narcotics. Anxiolytic and …

Objective To evaluate the efficacy and safety of lubiprostone in the treatment of chronic
idiopathic constipation (CIC) and irritable bowel syndrome with constipation (IBS-C) …

Background According to the multifactorial etiology of Irritable bowel syndrome (IBS),
psychological factors play an important role. It is possible that antidepressant therapy may …

Background and Objective. Irritable bowel syndrome (IBS) is a prevalent disorder of the
gastrointestinal system with complex pathogenesis. Shenling Baizhu powder (SLBZP) is a …

Introduction: Chronic constipation (CC) is a common gastrointestinal (GI) motility disorder
that significantly impairs the quality of life in affected subjects. As almost half of the patients …

Background Opioid receptors play a crucial role in the maintenance of homeostasis in the
gastrointestinal (GI) tract. The aim of this study was to characterize the effect of biphalin, a …

Introduction: Irritable bowel syndrome (IBS) is defined by symptoms of abdominal pain and
altered bowel habits without detectable organic disease. Antidepressants and serotonin …