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Principles and applications of nucleic acid strand displacement reactions
Dynamic DNA nanotechnology, a subfield of DNA nanotechnology, is concerned with the
study and application of nucleic acid strand-displacement reactions. Strand-displacement …
study and application of nucleic acid strand-displacement reactions. Strand-displacement …
Advanced photosensitizer activation strategies for smarter photodynamic therapy beacons
Photodynamic therapy (PDT) is a clinical treatment in which a light‐absorbing drug called a
photosensitizer (PS) is combined with light and molecular oxygen to generate cytotoxic …
photosensitizer (PS) is combined with light and molecular oxygen to generate cytotoxic …
Self-assembling nucleic acid nanostructures functionalized with aptamers
Researchers have worked for many decades to master the rules of biomolecular design that
would allow artificial biopolymer complexes to self-assemble and function similarly to the …
would allow artificial biopolymer complexes to self-assemble and function similarly to the …
Aptamer-integrated DNA nanostructures for biosensing, bioimaging and cancer therapy
The combination of nanostructures with biomolecules leading to the generation of functional
nanosystems holds great promise for biotechnological and biomedical applications. As a …
nanosystems holds great promise for biotechnological and biomedical applications. As a …
Construction of a multiple-aptamer-based DNA logic device on live cell membranes via associative toehold activation for accurate cancer cell identification
The ability to accurately identify and isolate cells is the cornerstone of precise disease
diagnosis and therapies. A single-step cell identification method based on logic analysis of …
diagnosis and therapies. A single-step cell identification method based on logic analysis of …
Engineering a second‐order DNA logic‐gated nanorobot to sense and release on live cell membranes for multiplexed diagnosis and synergistic therapy
Tumor biomarker‐based theranostics have achieved broad interest and success in recent
years. However, single biomarker‐based recognition can cause false‐positive feedback …
years. However, single biomarker‐based recognition can cause false‐positive feedback …
A DNA Logic Circuit Equipped with a Biological Amplifier Loaded into Biomimetic ZIF‐8 Nanoparticles Enables Accurate Identification of Specific Cancers In Vivo
K Wei, M He, J Zhang, C Zhao, C Nie… - Angewandte …, 2023 - Wiley Online Library
DNA logic circuits (DLC) enable the accurate identification of specific cell types, such as
cancer cells, but they face the challenges of weak output signals and a lack of competent …
cancer cells, but they face the challenges of weak output signals and a lack of competent …
DNA nanotechnology from the test tube to the cell
Abstract The programmability of Watson–Crick base pairing, combined with a decrease in
the cost of synthesis, has made DNA a widely used material for the assembly of molecular …
the cost of synthesis, has made DNA a widely used material for the assembly of molecular …
The pathway to intelligence: using stimuli‐responsive materials as building blocks for constructing smart and functional systems
Abstract Systems that are intelligent have the ability to sense their surroundings, analyze,
and respond accordingly. In nature, many biological systems are considered intelligent (eg …
and respond accordingly. In nature, many biological systems are considered intelligent (eg …
Engineering a 3D DNA-logic gate nanomachine for bispecific recognition and computing on target cell surfaces
R Peng, X Zheng, Y Lyu, L Xu, X Zhang… - Journal of the …, 2018 - ACS Publications
Among the vast number of recognition molecules, DNA aptamers generated from cell-
SELEX exhibit unique properties for identifying cell membrane biomarkers, in particular …
SELEX exhibit unique properties for identifying cell membrane biomarkers, in particular …