Beyond just peptide antigens: the complex world of peptide-based cancer vaccines

AJ Stephens, NA Burgess-Brown, S Jiang - Frontiers in immunology, 2021 - frontiersin.org
Peptide-based cancer vaccines rely upon the strong activation of the adaptive immune
response to elicit its effector function. They have shown to be highly specific and safe, but …

Development of peptide‐based vaccines for cancer

N Abd-Aziz, CL Poh - Journal of oncology, 2022 - Wiley Online Library
Peptides cancer vaccines are designed based on the epitope peptides that can elicit
humoral and cellular immune responses targeting tumor‐associated antigens (TAAs) or …

[HTML][HTML] Breast cancer vaccines: New insights into immunomodulatory and nano-therapeutic approaches

F Davodabadi, M Sarhadi, J Arabpour, S Sargazi… - Journal of Controlled …, 2022 - Elsevier
Breast cancer (BC) is known to be a highly heterogeneous disease that is clinically
subdivided into four primary molecular subtypes, each having distinct morphology and …

Characterization of stability, safety and immunogenicity of the mRNA lipid nanoparticle vaccine Iribovax® against COVID-19 in nonhuman primates

P Zamani, M Mashreghi, MR Bazaz, S Zargari… - Journal of Controlled …, 2023 - Elsevier
Abstract mRNA-lipid nanoparticle (mRNA-LNP) vaccines have proved their efficacy,
versatility and unprecedented manufacturing speed during the COVID-19 pandemic. Here …

Drug delivery methods for cancer immunotherapy

E Pérez-Herrero, OL Lanier, N Krishnan… - Drug Delivery and …, 2024 - Springer
Despite the fact that numerous immunotherapy-based drugs have been approved by the
FDA for the treatment of primary and metastatic tumors, only a small proportion of the …

Emerging nanomedicines for effective breast cancer immunotherapy

A Bahreyni, Y Mohamud, H Luo - Journal of nanobiotechnology, 2020 - Springer
Breast cancer continues to be the most frequently diagnosed malignancy among women,
putting their life in jeopardy. Cancer immunotherapy is a novel approach with the ability to …

Prophylactic cancer vaccines engineered to elicit specific adaptive immune response

DW Crews, JA Dombroski, MR King - Frontiers in Oncology, 2021 - frontiersin.org
Vaccines have been used to prevent and eradicate different diseases for over 200 years,
and new vaccine technologies have the potential to prevent many common illnesses …

Redox-sensitive doxorubicin liposome: A formulation approach for targeted tumor therapy

E Mirhadi, M Mashreghi, A Askarizadeh, A Mehrabian… - Scientific reports, 2022 - nature.com
In this study redox-sensitive (RS) liposomes manufactured using 10, 10′-diselanediylbis
decanoic acid (DDA), an organoselenium RS compound, to enhance the therapeutic …

Improving the efficacy of peptide vaccines in cancer immunotherapy

F Zahedipour, K Jamialahmadi, P Zamani… - International …, 2023 - Elsevier
Peptide vaccines have shown great potential in cancer immunotherapy by targeting tumor
antigens and activating the patient's immune system to mount a specific response against …

A review on the development of bacterial multi-epitope recombinant protein vaccines via reverse vaccinology

Y Li, MHR Farhan, X Yang, Y Guo, Y Sui, J Chu… - International Journal of …, 2024 - Elsevier
Bacterial vaccines play a crucial role in combating bacterial infectious diseases. Apart from
the prevention of disease, bacterial vaccines also help to reduce the mortality rates in …