Effects of externally-applied, non-pharmacological interventions on Short-and long-term symptoms and inflammatory cytokine levels in patients with knee osteoarthritis …

Z Wang, H Xu, Z Wang, H Zhou, J Diao… - Frontiers in …, 2023 - frontiersin.org
Background With the continuous development of clinical medicine, an increasing number of
non-pharmacological interventions have been applied for the treatment of knee …

Efficacy and safety of corticosteroids, hyaluronic acid, and PRP and combination therapy for knee osteoarthritis: a systematic review and network meta-analysis

X Qiao, L Yan, Y Feng, X Li, K Zhang, Z Lv, C Xu… - BMC Musculoskeletal …, 2023 - Springer
Objective There are many injectable treatments for knee osteoarthritis with different
characteristics and effects, the aim is to understand which one can lead to better and safer …

The minimal clinically important difference changes greatly based on the different calculation methods

M Franceschini, A Boffa, E Pignotti… - … American Journal of …, 2023 - journals.sagepub.com
Background: The minimal clinically important difference (MCID) for patient-reported outcome
measures (PROMs) expresses both the extent of the improvement and the value that …

Leukocyte-rich versus leukocyte-poor platelet-rich plasma for the treatment of knee osteoarthritis: a double-blind randomized trial

A Di Martino, A Boffa, L Andriolo… - … American journal of …, 2022 - journals.sagepub.com
Background: Platelet-rich plasma (PRP) is gaining large interest in clinical practice as a
minimally invasive injective treatment for knee osteoarthritis (OA). Different preparation …

Clinical efficacy and safety of the intra-articular injection of autologous adipose-derived mesenchymal stem cells for knee osteoarthritis: a phase III, randomized …

KI Kim, MC Lee, JH Lee, YW Moon… - … American journal of …, 2023 - journals.sagepub.com
Background: Intra-articular injection of autologous culture-expanded adipose-derived
mesenchymal stem cells (ADMSCs) has introduced a promising treatment option for knee …

Multiple platelet-rich plasma injections are superior to single PRP injections or saline in osteoarthritis of the knee: the 2-year results of a randomized, double-blind …

A Yurtbay, F Say, H Çinka, A Ersoy - Archives of orthopaedic and trauma …, 2022 - Springer
Introduction The primary purposes of this study were to prove the efficacy of PRP injection
therapy on knee pain and functions by comparing patients with mild to moderate OA with a …

Platelet-rich plasma: fundamentals and clinical applications

AJ Sheean, AW Anz, JP Bradley - Arthroscopy, 2021 - arthroscopyjournal.org
Platelet-rich plasma (PRP) is perhaps the most widely studied of the biologic therapies, with
an ever-growing body of evidence supporting its safety and efficacy in decreasing …

Platelet rich plasma in the repair of articular cartilage injury: a narrative review

Y Liang, J Li, Y Wang, J He, L Chen, J Chu, H Wu - Cartilage, 2022 - journals.sagepub.com
Objective This paper reviews the research of platelet-rich plasma (PRP) in articular cartilage
injury repair, to assess the mechanism, utilization, and efficacy of PRP in the treatment of …

Role of platelets in osteoarthritis—updated systematic review and meta-analysis on the role of platelet-rich plasma in osteoarthritis

E Tramś, K Malesa, S Pomianowski, R Kamiński - Cells, 2022 - mdpi.com
Platelets are an essential component of hemostasis, with an increasing role in host
inflammatory processes in injured tissues. The reaction between receptors and vascular …

Engineering injectable hyaluronic acid-based adhesive hydrogels with anchored PRP to pattern the micro-environment to accelerate diabetic wound healing

W Duan, X **, Y Zhao, S Martin-Saldaña, S Li… - Carbohydrate …, 2024 - Elsevier
Diabetic wounds remain a global challenge due to disordered wound healing led by
inflammation, infection, oxidative stress, and delayed proliferation. Therefore, an ideal …