Neuromyelitis optica and the evolving spectrum of autoimmune aquaporin‐4 channelopathies: a decade later

SJ Pittock, CF Lucchinetti - Annals of the new York Academy of …, 2016 - Wiley Online Library
The discovery of AQP4‐IgG (a pathogenic antibody that targets the astrocytic water channel
aquaporin‐4), as the first sensitive and specific biomarker for any inflammatory central …

Aquaporin-4 autoimmunity

A Zekeridou, VA Lennon - Neuroimmunology & Neuroinflammation, 2015 - neurology.org
Neuromyelitis optica (NMO) and a related spectrum of inflammatory CNS disorders are
unified by detection of a serum autoantibody specific for the aquaporin-4 (AQP4) water …

Clinical profile of patients with paraneoplastic neuromyelitis optica spectrum disorder and aquaporin-4 antibodies

M Sepúlveda, N Sola-Valls, D Escudero… - Multiple Sclerosis …, 2018 - journals.sagepub.com
Background: In a minority of patients with neuromyelitis optica spectrum disorder (NMOSD)
and aquaporin-4 antibodies (AQP4-IgG), the disease has a paraneoplastic origin. It is …

Evaluation of comorbidities and health care resource use among patients with highly active neuromyelitis optica

MR Ajmera, A Boscoe, J Mauskopf, SD Candrilli… - Journal of the …, 2018 - Elsevier
Background Neuromyelitis optica (NMO) is characterized by unpredictable attacks on the
optic nerves and spinal cord, causing accumulations of neurological disability that may lead …

Neuromyelitis optica spectrum disorder (NMOSD) associated with cancer: a systematic review

S Shahmohammadi, R Doosti… - Multiple Sclerosis and …, 2021 - Elsevier
NMOSD is a disease shown to be highly associated with other diseases such as
autoimmune diseases. There are a few reports of this association with cancer. So, this …

Paraneoplastic neuromyelitis optica spectrum disorder associated with metastatic carcinoid expressing aquaporin-4

M Figueroa, Y Guo, A Tselis, SJ Pittock… - JAMA …, 2014 - jamanetwork.com
Importance Reports of neuromyelitis optica spectrum disorder (NMOSD) occurring in the
setting of neoplasia suggest that aquaporin-4 autoimmunity may in some cases have a …

Autoimmune AQP4 channelopathies and neuromyelitis optica spectrum disorders

SR Hinson, VA Lennon, SJ Pittock - Handbook of clinical neurology, 2016 - Elsevier
Neuromyelitis optica (NMO) spectrum disorders (SD) represent an evolving group of central
nervous system (CNS)-inflammatory autoimmune demyelinating diseases unified by a …

A comparison of pediatric and adult neuromyelitis optica spectrum disorders: A review of clinical manifestation, diagnosis, and treatment

SM Baghbanian, N Asgari, MA Sahraian… - Journal of the …, 2018 - Elsevier
Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune inflammatory disorder
of the central nervous system (CNS). Serum immunoglobulin G autoantibodies (NMO-IgG) …

Paraneoplastic neuromyelitis optica spectrum disorders: three new cases and a review of the literature

G Cai, D He, L Chu, Q Dai, Z Xu… - International Journal of …, 2016 - Taylor & Francis
Neuromyelitis optica spectrum disorders (NMOSD) occasionally develop in patients with
tumor in relation to aquaporin-4 IgG (AQP4-IgG), representing a new paraneoplastic …

AQP4‐IgG positive paraneoplastic NMOSD: A case report and review

M Ding, Y Lang, L Cui - Brain and Behavior, 2021 - Wiley Online Library
Introduction Neuromyelitis optica spectrum disorder (NMOSD; also known as Devic
syndrome) is a clinical syndrome of central nervous system characterized by immune …