Heat shock proteins: Biological functions, pathological roles, and therapeutic opportunities
The heat shock proteins (HSPs) are ubiquitous and conserved protein families in both
prokaryotic and eukaryotic organisms, and they maintain cellular proteostasis and protect …
prokaryotic and eukaryotic organisms, and they maintain cellular proteostasis and protect …
Poultry response to heat stress: Its physiological, metabolic, and genetic implications on meat production and quality including strategies to improve broiler production …
AH Nawaz, K Amoah, QY Leng, JH Zheng… - Frontiers in veterinary …, 2021 - frontiersin.org
The continuous increase in poultry production over the last decades to meet the high
growing demand and provide food security has attracted much concern due to the recent …
growing demand and provide food security has attracted much concern due to the recent …
Heat shock proteins as immunomodulants
Heat shock proteins (Hsps) are conserved molecules whose main role is to facilitate folding
of other proteins. Most Hsps are generally stress-inducible as they play a particularly …
of other proteins. Most Hsps are generally stress-inducible as they play a particularly …
Macromolecular crowding in vitro, in vivo, and in between
Biochemical processes take place in heterogeneous and highly volume-occupied or
crowded environments that can considerably influence the reactivity and distribution of …
crowded environments that can considerably influence the reactivity and distribution of …
Small heat shock proteins: Simplicity meets complexity
M Haslbeck, S Weinkauf, J Buchner - Journal of Biological Chemistry, 2019 - ASBMB
Small heat shock proteins (sHsps) are a ubiquitous and ancient family of ATP-independent
molecular chaperones. A key characteristic of sHsps is that they exist in ensembles of iso …
molecular chaperones. A key characteristic of sHsps is that they exist in ensembles of iso …
Modulators of 14-3-3 protein–protein interactions
LM Stevers, E Sijbesma, M Botta… - Journal of medicinal …, 2017 - ACS Publications
Direct interactions between proteins are essential for the regulation of their functions in
biological pathways. Targeting the complex network of protein–protein interactions (PPIs) …
biological pathways. Targeting the complex network of protein–protein interactions (PPIs) …
Mechanisms and functions of spatial protein quality control
A healthy proteome is essential for cell survival. Protein misfolding is linked to a rapidly
expanding list of human diseases, ranging from neurodegenerative diseases to aging and …
expanding list of human diseases, ranging from neurodegenerative diseases to aging and …
Heat shock proteins regulatory role in neurodevelopment
DJ Miller, PE Fort - Frontiers in neuroscience, 2018 - frontiersin.org
Heat shock proteins (Hsps) are a large family of molecular chaperones that are well-known
for their roles in protein maturation, re-folding and degradation. While some Hsps are …
for their roles in protein maturation, re-folding and degradation. While some Hsps are …
Small heat shock proteins, big impact on protein aggregation in neurodegenerative disease
JM Webster, AL Darling, VN Uversky… - Frontiers in …, 2019 - frontiersin.org
Misfolding, aggregation, and aberrant accumulation of proteins are central components in
the progression of neurodegenerative disease. Cellular molecular chaperone systems …
the progression of neurodegenerative disease. Cellular molecular chaperone systems …
Immunoadjuvants for cancer immunotherapy: A review of recent developments
Cancer immunotherapy evolved as a new treatment modality to eradicate tumor cells and
has gained in popularity after its successful clinical transition. By activating antigen …
has gained in popularity after its successful clinical transition. By activating antigen …