Cellular surface plasmon resonance-based detection of anti-HPA-1a antibody glycosylation in fetal and neonatal alloimmune thrombocytopenia
Z Szittner, AEH Bentlage, AR Temming… - Frontiers in …, 2023 - frontiersin.org
Fetal and neonatal alloimmune thrombocytopenia (FNAIT) can occur due to maternal IgG
antibodies targeting platelet antigens, causing life-threatening bleeding in the neonate …
antibodies targeting platelet antigens, causing life-threatening bleeding in the neonate …
Serum from half of patients with immune thrombocytopenia triggers macrophage phagocytosis of platelets
PAA Norris, Z Tawhidi, UJ Sachs… - Blood …, 2023 - ashpublications.org
Humoral antiplatelet factors, such as autoantibodies, are thought to primarily clear platelets
by triggering macrophage phagocytosis in immune thrombocytopenia (ITP). However, there …
by triggering macrophage phagocytosis in immune thrombocytopenia (ITP). However, there …
Antibodies from chlamydia-infected individuals facilitate phagocytosis via Fc receptors
Non-neutralizing functions of antibodies, including phagocytosis, may play a role in
Chlamydia trachomatis (CT) infection, but these functions have not been studied and assays …
Chlamydia trachomatis (CT) infection, but these functions have not been studied and assays …
Trogocytosis drives red blood cell antigen loss in association with antibody-mediated immune suppression
Red blood cell (RBC) alloimmunization to paternal antigens during pregnancy can cause
hemolytic disease of the fetus and newborn (HDFN). This severe and potentially fatal …
hemolytic disease of the fetus and newborn (HDFN). This severe and potentially fatal …
Human Fc gamma receptor IIIA blockade inhibits platelet destruction in a humanized murine model of ITP
L Gil Gonzalez, KD Won, Z Tawhidi… - Blood …, 2024 - ashpublications.org
Fc gamma receptor (FcγR) IIIA is an important receptor for immunoglobulin G (IgG) and is
involved in immune defense mechanisms as well as tissue destruction in some autoimmune …
involved in immune defense mechanisms as well as tissue destruction in some autoimmune …
Antagonism of the Platelet-Activating Factor Pathway Mitigates Inflammatory Adverse Events Driven by Anti-erythrocyte Antibody Therapy in Mice
Immune thrombocytopenia (ITP) is an autoimmune disease characterized by low platelet
counts primarily due to antiplatelet autoantibodies. Anti-D is a donor-derived polyclonal Ab …
counts primarily due to antiplatelet autoantibodies. Anti-D is a donor-derived polyclonal Ab …
[HTML][HTML] Bispecific immune cell engager enhances the anticancer activity of CD16+ NK cells and macrophages in vitro, and eliminates cancer metastasis in NK …
Background In a prior report, we detailed the isolation and engineering of a bispecific killer
cell engager, referred to as BiKE: E5C1. The BiKE: E5C1 exhibits high affinity/specificity for …
cell engager, referred to as BiKE: E5C1. The BiKE: E5C1 exhibits high affinity/specificity for …
[PDF][PDF] Differential Gene Expression Analysis of PMA Treated Pro-monocytic Cell Lines
AO Kama - 2023 - wiredspace.wits.ac.za
Abstract HL-60, THP-1, and U937 are model cell lines that can undergo myeloid
differentiation in vitro, allowing the study of myeloid cell function in drug metabolism …
differentiation in vitro, allowing the study of myeloid cell function in drug metabolism …