The use of digital twins to represent a product or process digitally is trending in many
engineering disciplines. This term has also been recently introduced in the medical field. In …

Background Musculoskeletal soft tissues, such as articular cartilage, ligaments, knee
meniscus and intervertebral disk, have a complex structure, which provides elasticity and …

Muscles are the actuators that drive human movement. However, despite many decades of
work, we still cannot readily assess the forces that muscles transmit during human …

We present here a three-dimensional FE model of the healthy human knee that included the
main structures of the joint: bones, all the relevant ligaments and patellar tendon, menisci …

The prediction of the stress-state and fracture risk induced in bones by various loading
conditions in individual patients using subject-specific finite element models still represents …

Although intrinsic and extrinsic risk factors for anterior cruciate ligament (ACL) injury have
been explored extensively, the factors surrounding the inciting event and the biomechanical …

Many biomedical, orthopaedic, and industrial applications are emerging that will benefit from
personalized neuromusculoskeletal models. Applications include refined diagnostics …

Computational techniques and software for the analysis of problems in mechanics have
naturally moved from their origins in the traditional engineering disciplines to the study of …

Medial collateral ligament (MCL) injury is one of the most common knee injuries, especially
in young athletic patients. Most MCL injuries can be managed conservatively with good …

The topics of verification and validation have increasingly been discussed in the field of
computational biomechanics, and many recent articles have applied these concepts in an …