Exosome-driven nano-immunotherapy: revolutionizing colorectal cancer treatment

M Lahouty, M Fadaee, D Shanehbandi… - Molecular Biology …, 2025 - Springer
Colorectal cancer (CRC) ranks as the third most common cancer worldwide and remains a
major cause of cancer-related deaths, necessitating the development of innovative …

Exosomes in cancer diagnosis based on the Latest Evidence: Where are We?

K **, H Lan, Y Han, J Qian - International Immunopharmacology, 2024 - Elsevier
Exosomes are small extracellular vesicles (EVs) derived from various cellular sources and
have emerged as favorable biomarkers for cancer diagnosis and prognosis. These vesicles …

Advancements in Exosome Proteins for Breast Cancer Diagnosis and Detection: With a Focus on Nanotechnology

MJ Saadh, AMA Al-Rihaymee, M Kaur, A Kumar… - AAPS …, 2024 - Springer
Breast cancer, a leading cause of mortality among women, has been recognized as
requiring improved diagnostic methods. Exosome proteins, found in small extracellular …

Therapeutic combinations of exosomes alongside cancer stem cells (CSCs) and of CSC-derived exosomes (CSCEXs) in cancer therapy

A Zabeti Touchaei, SE Norollahi, A Najafizadeh… - Cancer Cell …, 2024 - Springer
Exosomes which are membrane vesicles released by cells have gained significant interest
in the field of cancer therapy as a novel means of intercellular communication. Their role in …

Triple-negative breast cancer-derived exosomes change the immunological features of human monocyte-derived dendritic cells and influence T-cell responses

S Safaei, S Alipour, SZ Bahojb Mahdavi… - Molecular Biology …, 2024 - Springer
Background Triple-negative breast cancer (TNBC) exhibits a lower survival rate in
comparison to other BC subtypes. Utilizing dendritic cell (DC) vaccines as a form of …

Enhancing the anti-tumor activity and reprogramming M2 macrophages by delivering siRNAs against SIRPα and STAT6 via M1 exosomes and combining with anti-PD …

M Taghavi-Farahabadi, M Mahmoudi, N Mojtabavi… - Life Sciences, 2025 - Elsevier
Background The invasive property of breast cancer and the complex composition of the
tumor microenvironment (TME) antibodies like anti-PD-L1, can inhibit tumor growth by …

Recent advancements and challenges in 3D bioprinting for cancer applications

SA Behera, B Nanda, PGR Achary - Bioprinting, 2024 - Elsevier
Abstract 3D bioprinting has emerged as a promising technology with transformative potential
in cancer research and therapy. This review explores the innovative applications …

Advancements in Colorectal Cancer Immunotherapy: From CAR-T Cells to Exosome-Based Therapies

S Arabi, M Fadaee, T Kazemi… - Journal of Drug …, 2025 - Taylor & Francis
Colorectal cancer (CRC) continues to be a major worldwide health issue, with elevated
death rates linked to late stages of the illness. Immunotherapy has made significant progress …

Extracellular Vesicles in Breast Cancer: From Intercellular Communication to Therapeutic Opportunities

B Muttiah, SL Ng, Y Lokanathan, MH Ng, JX Law - Pharmaceutics, 2024 - mdpi.com
Breast cancer, a multifaceted and heterogeneous disease, poses significant challenges in
terms of understanding its intricate resistance mechanisms and devising effective …

Exosomal ncRNAs in reproductive cancers

A Kowalczyk, M Wrzecińska, E Gałęska… - Biology of …, 2024 - academic.oup.com
Extracellular vesicles, particularly exosomes, play a pivotal role in the cellular mechanisms
underlying cancer. This review explores the various functions of exosomes in the …