Genome-wide association studies have identified hundreds of robust genetic associations
underlying psychiatric disorders and provided important biological insights into disease …

With progress in genome-wide association studies of depression, from identifying zero hits
in~ 16 000 individuals in 2013 to 223 hits in more than a million individuals in 2020 …

Biobanks often contain several phenotypes relevant to diseases such as major depressive
disorder (MDD), with partly distinct genetic architectures. Researchers face complex …

Genetic studies of human traits have revolutionized our understanding of the variation
between individuals, and yet, the genetics of most traits is still poorly understood. In this …

This review focuses on genome-wide association studies (GWASs) of asthma and allergic
diseases published between January 1, 2018, and June 30, 2019. During this time period …

Background Posttraumatic stress disorder (PTSD) is heritable and a potential consequence
of exposure to traumatic stress. Evidence suggests that a quantitative approach to PTSD …

Gene-environment interactions (GxE) can be fundamental in applications ranging from
functional genomics to precision medicine and is a conjectured source of substantial …

Genetic studies of metabolites have identified thousands of variants, many of which are
associated with downstream metabolic and obesogenic disorders. However, these studies …

Over the last decade, genome-wide association studies of psychiatric disorders have
identified numerous significant loci. Whereas these studies initially depended on cohorts …

Abstract Background Until now, Mendelian randomization (MR) studies have investigated
the causal association of risk factors with Alzheimer's disease (AD) using large-scale AD …