Nonequilibrium physics in biology

X Fang, K Kruse, T Lu, J Wang - Reviews of Modern Physics, 2019 - APS
Life is characterized by a myriad of complex dynamic processes allowing organisms to grow,
reproduce, and evolve. Physical approaches for describing systems out of thermodynamic …

The importance of water and hydraulic pressure in cell dynamics

Y Li, K Konstantopoulos, R Zhao, Y Mori… - Journal of cell …, 2020 - journals.biologists.com
All mammalian cells live in the aqueous medium, yet for many cell biologists, water is a
passive arena in which proteins are the leading players that carry out essential biological …

Defining the rate-limiting processes of bacterial cytokinesis

C Coltharp, J Buss, TM Plumer… - Proceedings of the …, 2016 - National Acad Sciences
Bacterial cytokinesis is accomplished by the essential 'divisome'machinery. The most widely
conserved divisome component, FtsZ, is a tubulin homolog that polymerizes into the 'FtsZ …

Bending forces plastically deform growing bacterial cell walls

A Amir, F Babaeipour, DB McIntosh… - Proceedings of the …, 2014 - National Acad Sciences
Cell walls define a cell's shape in bacteria. The walls are rigid to resist large internal
pressures, but remarkably plastic to adapt to a wide range of external forces and geometric …

Escherichia coli Peptidoglycan Structure and Mechanics as Predicted by Atomic-Scale Simulations

JC Gumbart, M Beeby, GJ Jensen… - PLoS computational …, 2014 - journals.plos.org
Bacteria face the challenging requirement to maintain their shape and avoid rupture due to
the high internal turgor pressure, but simultaneously permit the import and export of …

Requirement of essential Pbp2x and GpsB for septal ring closure in Streptococcus pneumoniae D39

AD Land, HCT Tsui, O Kocaoglu, SA Vella… - Molecular …, 2013 - Wiley Online Library
Bacterial cell shapes are manifestations of programs carried out by multi‐protein machines
that synthesize and remodel the resilient peptidoglycan (PG) mesh and other polymers …

How and why cells grow as rods

F Chang, KC Huang - BMC biology, 2014 - Springer
The rod is a ubiquitous shape adopted by walled cells from diverse organisms ranging from
bacteria to fungi to plants. Although rod-like shapes are found in cells of vastly different sizes …

Protecting from envelope stress: variations on the phage-shock-protein theme

R Manganelli, ML Gennaro - Trends in microbiology, 2017 - cell.com
During envelope stress, critical inner-membrane functions are preserved by the phage-
shock-protein (Psp) system, a stress response that emerged from work with Escherichia coli …

Bacterial division proteins FtsZ and ZipA induce vesicle shrinkage and cell membrane invagination

EJ Cabré, A Sánchez-Gorostiaga, P Carrara… - Journal of Biological …, 2013 - ASBMB
Permeable vesicles containing the proto-ring anchoring ZipA protein shrink when FtsZ, the
main cell division protein, polymerizes in the presence of GTP. Shrinkage, resembling the …

Systematic perturbation of cytoskeletal function reveals a linear scaling relationship between cell geometry and fitness

RD Monds, TK Lee, A Colavin, T Ursell, S Quan… - Cell reports, 2014 - cell.com
Diversification of cell size is hypothesized to have occurred through a process of
evolutionary optimization, but direct demonstrations of causal relationships between cell …