Mechanical regulation of cardiac development

SE Lindsey, JT Butcher, HC Yalcin - Frontiers in physiology, 2014 - frontiersin.org
Mechanical forces are essential contributors to and unavoidable components of cardiac
formation, both inducing and orchestrating local and global molecular and cellular changes …

4D flow MRI applications in congenital heart disease

J Rizk - European Radiology, 2021 - Springer
Advances in the diagnosis and management of congenital heart disease (CHD) have
resulted in a growing population of patients surviving well into adulthood and requiring …

Evaluation of aortic blood flow and wall shear stress in aortic stenosis and its association with left ventricular remodeling

F von Knobelsdorff-Brenkenhoff… - Circulation …, 2016 - Am Heart Assoc
Background—Aortic stenosis (AS) leads to variable stress for the left ventricle (LV) and
consequently a broad range of LV remodeling. The aim of this study was to describe blood …

CMR in evaluating valvular heart disease: diagnosis, severity, and outcomes

SG Myerson - Cardiovascular Imaging, 2021 - jacc.org
Cardiac magnetic resonance (CMR) is a versatile imaging tool that brings much to the
assessment of valvular heart disease. Although it is best known for myocardial imaging …

Quantitative analysis of vortical blood flow in the thoracic aorta using 4D phase contrast MRI

J von Spiczak, G Crelier, D Giese, S Kozerke, D Maintz… - PloS one, 2015 - journals.plos.org
Introduction Phase contrast MRI allows for the examination of complex hemodynamics in the
heart and adjacent great vessels. Vortex flow patterns seem to play an important role in …

Blood flow characteristics in the ascending aorta after aortic valve replacement—a pilot study using 4D-flow MRI

F von Knobelsdorff-Brenkenhoff, RF Trauzeddel… - International journal of …, 2014 - Elsevier
Background Aortic remodeling after aortic valve replacement (AVR) might be influenced by
the postoperative blood flow pattern in the ascending aorta. This pilot study used flow …

A methodology to detect abnormal relative wall shear stress on the full surface of the thoracic aorta using four‐dimensional flow MRI

P Van Ooij, WV Potters, AJ Nederveen… - Magnetic resonance …, 2015 - Wiley Online Library
Purpose To compute cohort‐averaged wall shear stress (WSS) maps in the thoracic aorta of
patients with aortic dilatation or valvular stenosis and to detect abnormal regional WSS …

Correlation between geometric parameters of the left coronary artery and hemodynamic descriptors of atherosclerosis: FSI and statistical study

N Pinho, CF Castro, CC António, N Bettencourt… - Medical & biological …, 2019 - Springer
The hemodynamics conditioned by coronary geometry may play an important role in the
creation of a pro-atherogenic environment in specific locations of the coronary tree. The aim …

Deep learning based centerline-aggregated aortic hemodynamics: an efficient alternative to numerical modeling of hemodynamics

P Yevtushenko, L Goubergrits… - IEEE Journal of …, 2021 - ieeexplore.ieee.org
Image-based patient-specific modelling of hemodynamics are gaining increased popularity
as a diagnosis and outcome prediction solution for a variety of cardiovascular diseases …