Dysregulation of adult hippocampal neuroplasticity in major depression: pathogenesis and therapeutic implications

AN Tartt, MB Mariani, R Hen, JJ Mann… - Molecular psychiatry, 2022 - nature.com
Major depressive disorder (MDD) was previously hypothesized to be a disease of
monoamine deficiency in which low levels of monoamines in the synaptic cleft were …

BDNF signaling in context: From synaptic regulation to psychiatric disorders

CS Wang, ET Kavalali, LM Monteggia - Cell, 2022 - cell.com
Brain-derived neurotrophic factor (BDNF) is a neuropeptide that plays numerous important
roles in synaptic development and plasticity. While its importance in fundamental physiology …

Assessing the mechanisms of brain plasticity by transcranial magnetic stimulation

A Jannati, LM Oberman, A Rotenberg… - …, 2023 - nature.com
Transcranial magnetic stimulation (TMS) is a non-invasive technique for focal brain
stimulation based on electromagnetic induction where a fluctuating magnetic field induces a …

State-dependent effects of neural stimulation on brain function and cognition

C Bradley, AS Nydam, PE Dux… - Nature Reviews …, 2022 - nature.com
Invasive and non-invasive brain stimulation methods are widely used in neuroscience to
establish causal relationships between distinct brain regions and the sensory, cognitive and …

Non-invasive transcranial ultrasound stimulation for neuromodulation

G Darmani, TO Bergmann, KB Pauly, CF Caskey… - Clinical …, 2022 - Elsevier
Transcranial ultrasound stimulation (TUS) holds great potential as a tool to alter neural
circuits non-invasively in both animals and humans. In contrast to established non-invasive …

Synaptic plasticity forms and functions

JC Magee, C Grienberger - Annual review of neuroscience, 2020 - annualreviews.org
Synaptic plasticity, the activity-dependent change in neuronal connection strength, has long
been considered an important component of learning and memory. Computational and …

Bridging biological and artificial neural networks with emerging neuromorphic devices: fundamentals, progress, and challenges

J Tang, F Yuan, X Shen, Z Wang, M Rao… - Advanced …, 2019 - Wiley Online Library
As the research on artificial intelligence booms, there is broad interest in brain‐inspired
computing using novel neuromorphic devices. The potential of various emerging materials …

Synaptic plasticity and mental health: methods, challenges and opportunities

LG Appelbaum, MA Shenasa, L Stolz… - …, 2023 - nature.com
Activity-dependent synaptic plasticity is a ubiquitous property of the nervous system that
allows neurons to communicate and change their connections as a function of past …

The role of inhibitory circuits in hippocampal memory processing

L Topolnik, S Tamboli - Nature Reviews Neuroscience, 2022 - nature.com
GABAergic inhibitory circuits play an essential role in coordinating various hippocampal
functions. Several decades of work dedicated to a thorough characterization of hippocampal …

Synaptic memory and CaMKII

RA Nicoll, H Schulman - Physiological reviews, 2023 - journals.physiology.org
Ca2+/calmodulin-dependent protein kinase II (CaMKII) and long-term potentiation (LTP)
were discovered within a decade of each other and have been inextricably intertwined ever …