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Neuroimmune crosstalk in the cornea: The role of immune cells in corneal nerve maintenance during homeostasis and inflammation
In the cornea, resident immune cells are in close proximity to sensory nerves, consistent with
their important roles in the maintenance of nerves in both homeostasis and inflammation …
their important roles in the maintenance of nerves in both homeostasis and inflammation …
Redefining our vision: an updated guide to the ocular immune system
Balanced immune responses in the eyes are crucial to preserve vision. The ocular immune
system has long been considered distinct, owing to the so-called 'immune privilege'of its …
system has long been considered distinct, owing to the so-called 'immune privilege'of its …
Redefining the human corneal immune compartment using dynamic intravital imaging
The healthy human cornea is a uniquely transparent sensory tissue where immune
responses are tightly controlled to preserve vision. The cornea contains immune cells that …
responses are tightly controlled to preserve vision. The cornea contains immune cells that …
[HTML][HTML] Corneal tissue-resident memory T cells form a unique immune compartment at the ocular surface
The eye is considered immune privileged such that immune responses are dampened to
protect vision. As the most anterior compartment of the eye, the cornea is exposed to …
protect vision. As the most anterior compartment of the eye, the cornea is exposed to …
Potential ocular biomarkers for early detection of Alzheimer's disease and their roles in artificial intelligence studies
P Chaitanuwong, P Singhanetr, M Chainakul… - Neurology and …, 2023 - Springer
Alzheimer's disease (AD) is the leading cause of dementia worldwide. Early detection is
believed to be essential to disease management because it enables physicians to initiate …
believed to be essential to disease management because it enables physicians to initiate …
Ophthalmic biomarkers for Alzheimer's disease: A review
A Majeed, B Marwick, H Yu, H Fadavi… - Frontiers in aging …, 2021 - frontiersin.org
Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by
neuronal loss, extracellular amyloid-β (Aβ) plaques, and intracellular neurofibrillary tau …
neuronal loss, extracellular amyloid-β (Aβ) plaques, and intracellular neurofibrillary tau …
Corneal immune cell morphometry as an indicator of local and systemic pathology: a review
HR Chinnery, XY Zhang, CY Wu… - Clinical & experimental …, 2021 - Wiley Online Library
The corneal epithelium contains a population of resident immune cells commonly referred to
as dendritic cells (DCs), or Langerhans cells. A unique advantage of the transparent cornea …
as dendritic cells (DCs), or Langerhans cells. A unique advantage of the transparent cornea …
Intravital imaging of the human cornea reveals the differential effects of season on innate and adaptive immune cell morphodynamics
Purpose Defining how the in vivo immune status of peripheral tissues is shaped by the
external environment has remained a technical challenge. We recently developed …
external environment has remained a technical challenge. We recently developed …
Oculomics: a crusade against the four horsemen of chronic disease
EJ Patterson, AD Bounds, SK Wagner… - Ophthalmology and …, 2024 - Springer
Chronic, non-communicable diseases present a major barrier to living a long and healthy
life. In many cases, early diagnosis can facilitate prevention, monitoring, and treatment …
life. In many cases, early diagnosis can facilitate prevention, monitoring, and treatment …
Corneal nerve loss predicts dementia in patients with mild cognitive impairment
G Ponirakis, H Al Hamad, DAM Omar… - Annals of Clinical …, 2023 - Wiley Online Library
Objectives This study compared the utility of corneal nerve measures with brain volumetry
for predicting progression to dementia in individuals with mild cognitive impairment (MCI) …
for predicting progression to dementia in individuals with mild cognitive impairment (MCI) …