Synthetic biology: bottom-up assembly of molecular systems

S Hirschi, TR Ward, WP Meier, DJ Müller… - Chemical …, 2022 - ACS Publications
The bottom-up assembly of biological and chemical components opens exciting
opportunities to engineer artificial vesicular systems for applications with previously unmet …

Interface engineering in multiphase systems toward synthetic cells and organelles: From soft matter fundamentals to biomedical applications

Z Liu, W Zhou, C Qi, T Kong - Advanced Materials, 2020 - Wiley Online Library
Synthetic cells have a major role in gaining insight into the complex biological processes of
living cells; they also give rise to a range of emerging applications from gene delivery to …

Macromolecular design and preparation of polymersomes

J Lefley, C Waldron, CR Becer - Polymer Chemistry, 2020 - pubs.rsc.org
From drug delivery to nanoreactors and protocells, polymersomes have gained
considerable interest from researchers due to their novel applications. However, one of the …

Heterogeneous synthetic vesicles toward artificial cells: engineering structure and composition of membranes for multimodal functionalities

J Shin, BD Cole, T Shan, Y Jang - Biomacromolecules, 2022 - ACS Publications
The desire to develop artificial cells to imitate living cells in synthetic vesicle platforms has
continuously increased over the past few decades. In particular, heterogeneous synthetic …

Light‐Driven Proton Transfer for Cyclic and Temporal Switching of Enzymatic Nanoreactors

S Moreno, P Sharan, J Engelke, H Gumz, S Boye… - Small, 2020 - Wiley Online Library
Temporal activation of biological processes by visible light and subsequent return to an
inactive state in the absence of light is an essential characteristic of photoreceptor cells …

Application of polymersomes in membrane protein study and drug discovery: Progress, strategies, and perspectives

CH Lo, J Zeng - Bioengineering & translational medicine, 2023 - Wiley Online Library
Membrane proteins (MPs) play key roles in cellular signaling pathways and are responsible
for intercellular and intracellular interactions. Dysfunctional MPs are directly related to the …

Synthesis and complex self-assembly of amphiphilic block copolymers with a branched hydrophobic poly (2-oxazoline) into multicompartment micelles, pseudo …

D Daubian, J Gaitzsch, W Meier - Polymer Chemistry, 2020 - pubs.rsc.org
We report on the synthesis and self-assembly of poly (ethylene oxide)-block-poly (2-(3-
ethylheptyl)-2-oxazoline)(PEO-b-PEHOx), a new amphiphilic diblock copolymer obtained via …

Visible Light‐ATRP Driven by Tris (2‐Pyridylmethyl) Amine (TPMA) Impurities in the Open Air

AM Jazani, DJ Schild, J Sobieski, X Hu… - Macromolecular …, 2023 - Wiley Online Library
Atom transfer radical polymerization (ATRP) of oligo (ethylene oxide) monomethyl ether
methacrylate (OEOMA500) in water is enabled using CuBr2 with tris (2‐pyridylmethyl) amine …

Stretched or wrinkled? Looking into the polymer conformation within polymersome membranes

C Effenberg, J Gaitzsch - Soft Matter, 2024 - pubs.rsc.org
Self-assembly of amphiphilic block-copolymers into polymersomes is a well-established
concept. In this membrane, the hydrophilic part is considered to be loosely assembled …

Artificial Organelles with Orthogonal‐Responsive Membranes for Protocell Systems: Probing the Intrinsic and Sequential Docking and Diffusion of Cargo into Two …

X Wang, S Moreno, S Boye, P Wang, X Liu… - Advanced …, 2021 - Wiley Online Library
The challenge of effective integration and use of artificial organelles with orthogonal‐
responsive membranes and their communication in eukaryotic protocells is to understand …