Antimicrobial photodynamic therapy to control clinically relevant biofilm infections

X Hu, YY Huang, Y Wang, X Wang… - Frontiers in …, 2018 - frontiersin.org
Biofilm describes a microbially-derived sessile community in which microbial cells are firmly
attached to the substratum and embedded in extracellular polymeric matrix. Microbial …

Treatment of Pseudomonas aeruginosa infectious biofilms: Challenges and strategies

R Yin, J Cheng, J Wang, P Li, J Lin - Frontiers in Microbiology, 2022 - frontiersin.org
Pseudomonas aeruginosa, a Gram-negative bacterium, is one of the major pathogens
implicated in human opportunistic infection and a common cause of clinically persistent …

Photodynamic and antibiotic therapy in combination against bacterial infections: efficacy, determinants, mechanisms, and future perspectives

Y Feng, CC Tonon, S Ashraf, T Hasan - Advanced Drug Delivery Reviews, 2021 - Elsevier
Antibiotic treatment, the mainstay for the control of bacterial infections, is greatly hampered
by the global prevalence of multidrug-resistant (MDR) bacteria. Photodynamic therapy (PDT) …

Antibacterial photodynamic therapy: overview of a promising approach to fight antibiotic-resistant bacterial infections

Y Liu, R Qin, SAJ Zaat, E Breukink… - Journal of clinical and …, 2015 - pmc.ncbi.nlm.nih.gov
Antibacterial photodynamic therapy (APDT) has drawn increasing attention from the
scientific society for its potential to effectively kill multidrug-resistant pathogenic bacteria and …

Porphyrinoid photosensitizers mediated photodynamic inactivation against bacteria

L Sobotta, P Skupin-Mrugalska, J Piskorz… - European journal of …, 2019 - Elsevier
The multi-drug resistant bacteria have become a serious problem complicating therapies to
such a degree that often the term “post-antibiotic era” is applied to describe the situation …

Resistance in antimicrobial photodynamic inactivation of bacteria

T Maisch - Photochemical & Photobiological Sciences, 2015 - Springer
Antibiotics have increasingly lost their impact to kill bacteria efficiently during the last 10
years. The emergence and dissemination of superbugs with resistance to multiple antibiotic …

[HTML][HTML] Riboflavin as a promising antimicrobial agent? A multi-perspective review

N Farah, VK Chin, PP Chong, WF Lim, CW Lim… - Current Research in …, 2022 - Elsevier
Riboflavin, or more commonly known as vitamin B2, forms part of the component of vitamin B
complex. Riboflavin consisting of two important cofactors, flavin mononucleotide (FMN) and …

An insight on bacterial cellular targets of photodynamic inactivation

E Alves, MAF Faustino, MG Neves… - Future medicinal …, 2014 - Taylor & Francis
The emergence of microbial resistance is becoming a global problem in clinical and
environmental areas. As such, the development of drugs with novel modes of action will be …

Conjugation of antimicrobial peptides to enhance therapeutic efficacy

SP Selvaraj, JY Chen - European Journal of Medicinal Chemistry, 2023 - Elsevier
The growing prevalence of antimicrobial resistance (AMR) has brought with it a continual
increase in the numbers of deaths from multidrug-resistant (MDR) infections. Since the …

Factors determining the susceptibility of bacteria to antibacterial photodynamic inactivation

A Rapacka-Zdończyk, A Woźniak, K Michalska… - Frontiers in …, 2021 - frontiersin.org
Photodynamic inactivation of microorganisms (aPDI) is an excellent method to destroy
antibiotic-resistant microbial isolates. The use of an exogenous photosensitizer or irradiation …