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Vitiligo: a review
Vitiligo, a common depigmenting skin disorder, has an estimated prevalence of 0.5–2% of
the population worldwide. The disease is characterized by the selective loss of melanocytes …
the population worldwide. The disease is characterized by the selective loss of melanocytes …
Update on the pathogenesis of vitiligo
HZ Marchioro, CCS Castro, VM Fava… - Anais brasileiros de …, 2022 - SciELO Brasil
Vitiligo is a complex disease whose pathogenesis results from the interaction of genetic
components, metabolic factors linked to cellular oxidative stress, melanocyte adhesion to the …
components, metabolic factors linked to cellular oxidative stress, melanocyte adhesion to the …
Complex genetic signatures in immune cells underlie autoimmunity and inform therapy
We report on the influence of~ 22 million variants on 731 immune cell traits in a cohort of
3,757 Sardinians. We detected 122 significant (P< 1.28× 10− 11) independent association …
3,757 Sardinians. We detected 122 significant (P< 1.28× 10− 11) independent association …
Revisiting IL-2: Biology and therapeutic prospects
Interleukin-2 (IL-2), the first cytokine that was molecularly cloned, was shown to be a T cell
growth factor essential for the proliferation of T cells and the generation of effector and …
growth factor essential for the proliferation of T cells and the generation of effector and …
Mechanisms of melanocyte death in vitiligo
J Chen, S Li, C Li - Medicinal Research Reviews, 2021 - Wiley Online Library
Vitiligo is an autoimmune depigment disease results from extensive melanocytes
destruction. The destruction of melanocyte is thought to be of multifactorial causation …
destruction. The destruction of melanocyte is thought to be of multifactorial causation …
Vitiligo: a focus on pathogenesis and its therapeutic implications
Vitiligo is the most common depigmenting disorder affecting 0.1%–2% of the population
worldwide. The characteristic white patches result from the selective loss of melanocytes …
worldwide. The characteristic white patches result from the selective loss of melanocytes …
Vitiligo, from pathogenesis to therapeutic advances: state of the art
F Diotallevi, H Gioacchini, E De Simoni… - International Journal of …, 2023 - mdpi.com
Vitiligo is an acquired hypopigmentation of the skin due to a progressive selective loss of
melanocytes; it has a prevalence of 1–2% and appears as rounded, well-demarcated white …
melanocytes; it has a prevalence of 1–2% and appears as rounded, well-demarcated white …
Genome-wide association studies of autoimmune vitiligo identify 23 new risk loci and highlight key pathways and regulatory variants
Vitiligo is an autoimmune disease in which depigmented skin results from the destruction of
melanocytes, with epidemiological association with other autoimmune diseases. In previous …
melanocytes, with epidemiological association with other autoimmune diseases. In previous …
Vitiligo treatments: review of current therapeutic modalities and JAK inhibitors
KN Cunningham, D Rosmarin - American journal of clinical dermatology, 2023 - Springer
Vitiligo is a chronic autoimmune disease characterized by loss of pigment of the skin,
affecting 0.5–2% of the population worldwide. It can have a significant impact on patients' …
affecting 0.5–2% of the population worldwide. It can have a significant impact on patients' …
Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease
More than 1,000 susceptibility loci have been identified through genome-wide association
studies (GWAS) of common variants; however, the specific genes and full allelic spectrum of …
studies (GWAS) of common variants; however, the specific genes and full allelic spectrum of …