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[HTML][HTML] Cardiac transmembrane ion channels and action potentials: cellular physiology and arrhythmogenic behavior
Cardiac arrhythmias are among the leading causes of mortality. They often arise from
alterations in the electrophysiological properties of cardiac cells and their underlying ionic …
alterations in the electrophysiological properties of cardiac cells and their underlying ionic …
Guidelines for assessment of cardiac electrophysiology and arrhythmias in small animals
Cardiac arrhythmias are a major cause of morbidity and mortality worldwide. Although
recent advances in cell-based models, including human-induced pluripotent stem cell …
recent advances in cell-based models, including human-induced pluripotent stem cell …
Human ES-cell-derived cardiomyocytes electrically couple and suppress arrhythmias in injured hearts
Transplantation studies in mice and rats have shown that human embryonic-stem-cell-
derived cardiomyocytes (hESC-CMs) can improve the function of infarcted hearts,,, but two …
derived cardiomyocytes (hESC-CMs) can improve the function of infarcted hearts,,, but two …
The role of extracellular matrix composition in structure and function of bioengineered skeletal muscle
One of the obstacles to the potential clinical utility of bioengineered skeletal muscle is its
limited force generation capacity. Since engineered muscle, unlike most native muscle …
limited force generation capacity. Since engineered muscle, unlike most native muscle …
Controlling the contractile strength of engineered cardiac muscle by hierarchal tissue architecture
The heart is a muscular organ with a wrap**, laminar structure embedded with neural and
vascular networks, collagen fibrils, fibroblasts, and cardiac myocytes that facilitate …
vascular networks, collagen fibrils, fibroblasts, and cardiac myocytes that facilitate …
Transmural dispersion of repolarization in failing and nonfailing human ventricle
Rationale: Transmural dispersion of repolarization has been shown to play a role in the
genesis of ventricular tachycardia and fibrillation in different animal models of heart failure …
genesis of ventricular tachycardia and fibrillation in different animal models of heart failure …
Cardiac electrophysiology in mice: a matter of size
S Kaese, S Verheule - Frontiers in physiology, 2012 - frontiersin.org
Over the last decade, mouse models have become a popular instrument for studying cardiac
arrhythmias. This review assesses in which respects a mouse heart is a miniature human …
arrhythmias. This review assesses in which respects a mouse heart is a miniature human …