Nanoparticles in photodynamic therapy

SS Lucky, KC Soo, Y Zhang - Chemical reviews, 2015 - ACS Publications
Cancer accounted for 7.6 million deaths (around 13% of all deaths) worldwide in 2008.(1)
Almost 13 million cancer cases are newly diagnosed every year, and deaths are projected to …

Overcoming the Achilles' heel of photodynamic therapy

W Fan, P Huang, X Chen - Chemical Society Reviews, 2016 - pubs.rsc.org
Photodynamic therapy (PDT) has been applied to treat a wide range of medical conditions,
including wet age-related macular degeneration psoriasis, atherosclerosis, viral infection …

Nanochemistry and nanomedicine for nanoparticle-based diagnostics and therapy

G Chen, I Roy, C Yang, PN Prasad - Chemical reviews, 2016 - ACS Publications
Nanoparticles are generally defined as any particulate material for which at least one
dimension lies in the range of 1− 100 nm. 1− 3 They can exist in various shapes, such as …

Photosensitizers with aggregation‐induced emission: materials and biomedical applications

F Hu, S Xu, B Liu - Advanced materials, 2018 - Wiley Online Library
Photodynamic therapy is arising as a noninvasive treatment modality for cancer and other
diseases. One of the key factors to determine the therapeutic function is the efficiency of …

Nanomaterials for theranostics: recent advances and future challenges

EK Lim, T Kim, S Paik, S Haam, YM Huh… - Chemical reviews, 2015 - ACS Publications
In 2004, the US Food and Drug Administration (FDA) released an important report entitled
“Innovation/Stagnation: Challenge and Opportunity on the Critical Path to New Medical …

In vivo photodynamic therapy using upconversion nanoparticles as remote-controlled nanotransducers

NM Idris, MK Gnanasammandhan, J Zhang, PC Ho… - Nature medicine, 2012 - nature.com
Conventional photodynamic therapy (PDT) is limited by the penetration depth of visible light
needed for its activation. Here we used mesoporous-silica–coated upconversion fluorescent …

Micro/nanoparticle‐augmented sonodynamic therapy (SDT): breaking the depth shallow of photoactivation

X Qian, Y Zheng, Y Chen - Advanced materials, 2016 - Wiley Online Library
The fast development of photoactivation for cancer treatment provides an efficient photo‐
therapeutic strategy for cancer treatment, but traditional photodynamic or photothermal …

Highly fluorescent semiconducting polymer dots for biology and medicine

C Wu, DT Chiu - Angewandte Chemie International Edition, 2013 - Wiley Online Library
In recent years, semiconducting polymer nanoparticles have attracted considerable attention
because of their outstanding characteristics as fluorescent probes. These nanoparticles …

The development of microgels/nanogels for drug delivery applications

JK Oh, R Drumright, DJ Siegwart… - Progress in polymer …, 2008 - Elsevier
Microgels/nanogels are crosslinked polymeric particles, which can be considered as
hydrogels if they are composed of water soluble/swellable polymer chains. They possess …

Design and challenges of sonodynamic therapy system for cancer theranostics: from equipment to sensitizers

Z Gong, Z Dai - Advanced Science, 2021 - Wiley Online Library
As a novel noninvasive therapeutic modality combining low‐intensity ultrasound and
sonosensitizers, sonodynamic therapy (SDT) is promising for clinical translation due to its …