The burden of hepatocellular carcinoma (HCC) is highest in East Asia and Africa, although
its incidence and mortality are rapidly rising in the United States and Europe. With the …

Due to an increase in the obesity-associated metabolic syndrome of epidemic proportions,
nonalcoholic fatty liver disease (NAFLD) is becoming a leading cause of hepatocellular …

Hepatocellular carcinoma (HCC) development entails changes in liver metabolism. Current
knowledge on metabolic perturbations in HCC is derived mostly from case‐control designs …

Background and Aim: Alpha-fetoprotein (AFP), a lens culinaris agglutinin-reactive fraction of
AFP (AFP-L3), is a protein that is induced by vitamin K deficiency or antagonist-II (PIVKA-II) …

Importance Non-alcoholic fatty liver disease (NAFLD) is a rapidly growing cause of chronic
liver disease and is becoming a leading cause of hepatocellular carcinoma (HCC) in many …

Background Northern England has been experiencing a persistent rise in the number of
primary liver cancers, largely driven by an increasing incidence of hepatocellular carcinoma …

Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver
diseases in developed countries, and its prevalence and incidence are rapidly increasing …

Potential conflict of interest: Dr. Hopkin consults for, advises for, is on the speakers' bureau
for, and received grants from Sanofi Genzyme and Alexion. He consults for, advises for, and …

Hepatocellular carcinoma (HCC) is the most frequently found primary malignancy of the
liver, showing an accelerated upward trend over the past few years and exhibiting an …

Background Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver
disease showing a rising prevalence globally. Genetic predisposition plays a key role in the …