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[HTML][HTML] Glia–neuron interactions in the mammalian retina
The mammalian retina provides an excellent opportunity to study glia–neuron interactions
and the interactions of glia with blood vessels. Three main types of glial cells are found in …
and the interactions of glia with blood vessels. Three main types of glial cells are found in …
Functional architecture of the retina: development and disease
Abstract Structure and function are highly correlated in the vertebrate retina, a sensory tissue
that is organized into cell layers with microcircuits working in parallel and together to encode …
that is organized into cell layers with microcircuits working in parallel and together to encode …
Stimulation of functional neuronal regeneration from Müller glia in adult mice
Many retinal diseases lead to the loss of retinal neurons and cause visual impairment. The
adult mammalian retina has little capacity for regeneration. By contrast, teleost fish …
adult mammalian retina has little capacity for regeneration. By contrast, teleost fish …
Reprogramming Müller glia to regenerate ganglion-like cells in adult mouse retina with developmental transcription factors
Many neurodegenerative diseases cause degeneration of specific types of neurons. For
example, glaucoma leads to death of retinal ganglion cells, leaving other neurons intact …
example, glaucoma leads to death of retinal ganglion cells, leaving other neurons intact …
Müller glial cell reprogramming and retina regeneration
D Goldman - Nature Reviews Neuroscience, 2014 - nature.com
Müller glia are the major glial component of the retina. They are one of the last retinal cell
types to be born during development, and they function to maintain retinal homeostasis and …
types to be born during development, and they function to maintain retinal homeostasis and …
Evaluating cell reprogramming, differentiation and conversion technologies in neuroscience
The scarcity of live human brain cells for experimental access has for a long time limited our
ability to study complex human neurological disorders and elucidate basic neuroscientific …
ability to study complex human neurological disorders and elucidate basic neuroscientific …
In vivo cellular reprogramming: the next generation
Cellular reprogramming technology has created new opportunities in understanding human
disease, drug discovery, and regenerative medicine. While a combinatorial code was …
disease, drug discovery, and regenerative medicine. While a combinatorial code was …
Age‐related macular degeneration: new paradigms for treatment and management of AMD
LF Hernández-Zimbrón… - Oxidative medicine …, 2018 - Wiley Online Library
Age‐related macular degeneration (AMD) is a well‐characterized and extensively studied
disease. It is currently considered the leading cause of visual disability among patients over …
disease. It is currently considered the leading cause of visual disability among patients over …
[HTML][HTML] bHLH transcription factors in neural development, disease, and reprogramming
DJ Dennis, S Han, C Schuurmans - Brain research, 2019 - Elsevier
The formation of functional neural circuits in the vertebrate central nervous system (CNS)
requires that appropriate numbers of the correct types of neuronal and glial cells are …
requires that appropriate numbers of the correct types of neuronal and glial cells are …
Reprogramming Müller glia to regenerate retinal neurons
M Lahne, M Nagashima, DR Hyde… - Annual Review of …, 2020 - annualreviews.org
In humans, various genetic defects or age-related diseases, such as diabetic retinopathies,
glaucoma, and macular degeneration, cause the death of retinal neurons and profound …
glaucoma, and macular degeneration, cause the death of retinal neurons and profound …