Clostridium difficile is the prominent etiological agent of healthcare-associated diarrhea. The
disease symptoms range from mild diarrhea to life-threatening pseudomembranous colitis …

Clostridioides difficile is often resistant to the actions of antibiotics to treat other bacterial
infections and the resulting C. difficile infection (CDI) is among the leading causes of …

The aim of this study was to determine whether Lactobacillus rhamnosus GG (LGG)
components (surface layer protein, SLP; genomic DNA, gDNA; unmethylated cytosine …

The spectrum of Clostridium difficile infections is highly variable, ranging from asymptomatic
carriage to fatal colitis depending on the strain virulence and on the host, its gut microbiota …

In bacteria, as in other microorganisms, surface compounds interact with different pattern
recognition receptors expressed by host cells, which usually triggers a variety of cellular …

Clostridioides difficile infection (CDI) is a common cause of antibiotic-associated colitis. C.
difficile proliferates and produces toxins that damage the colonic epithelium, leading to …

Background Surface layer protein A (SlpA), the primary outermost structure of Clostridioides
difficile, plays an essential role in C. difficile pathogenesis, although its interaction with host …

Clostridioides difficile (C. difficile) is the major cause of hospital-acquired gastrointestinal
infections in individuals following antibiotics treatment. The pathogenesis of C. difficile …

Clostridium difficile is a major causative agent of antibiotic-associated diarrhea and has
become the most common pathogen of healthcare-associated infection worldwide. The …

Clostridioides difficile is the leading cause of healthcare-and antibiotic-associated diarrhea.
Surface layer protein A (SlpA), an essential component of the bacterium's outermost layer …