Caspases are a family of proteases that play critical roles in controlling inflammation and cell
death. Apoptosis is a caspase-3 mainly controlled behavior to avoid inflammation and …

Caspase-3 plays irreplaceable roles in apoptosis and related diseases. An imbalance in the
measured levels of Caspase-3 is implicated in irreversible apoptosis. Therefore, the …

Epstein–Barr virus (EBV) was first discovered in cells from a patient with Burkitt lymphoma
(BL), and is now known to be a contributory factor in 1–2% of all cancers, for which there are …

Glucose metabolism and DNA repair are fundamental cellular processes frequently
dysregulated in cancer. In this study, we define a direct role for the glycolytic Aldolase A …

Abstract SASH1 (SAM and SH3 domain-containing protein 1) is a tumor suppressor protein
that has roles in key cellular processes including apoptosis and cellular proliferation. As …

Micro (mi) RNAs serve crucial roles in cancer development although little is known about
their cellular mechanisms in the pathogenesis of melanoma. The present study explored the …

Intracellular adaptor proteins are indispensable for the transduction of receptor‐derived
signals, as they recruit and connect essential downstream effectors. The SLy/SASH1 …

Triple-negative breast cancer (TNBC) is extremely aggressive and lacks effective therapy.
SAM and SH3 domain containing1 (SASH1) has been implicated in TNBC as a candidate …

Calcium/calmodulin‐dependent serine protein kinase (CASK) interaction protein 1/2
(Caskin1/2) is essential neuronal synaptic scaffold protein in nervous system development …

Host organisms use different innate immune mechanisms to defend against pathogenic
infections, while tight control of innate immunity is essential for proper immune induction and …