Antibody-mediated encephalitis
J Dalmau, F Graus - New England Journal of Medicine, 2018 - Mass Medical Soc
Antibody-Mediated Encephalitis The category of autoimmune encephalitides constitutes
disorders with relatively distinct characteristics such as psychosis, seizures, abnormal …
disorders with relatively distinct characteristics such as psychosis, seizures, abnormal …
Autoimmune psychosis: an international consensus on an approach to the diagnosis and management of psychosis of suspected autoimmune origin
There is increasing recognition in the neurological and psychiatric literature of patients with
so-called isolated psychotic presentations (ie, with no, or minimal, neurological features) …
so-called isolated psychotic presentations (ie, with no, or minimal, neurological features) …
Autoimmune encephalitis epidemiology and a comparison to infectious encephalitis
Objective To evaluate the incidence and prevalence of autoimmune encephalitis and
compare it to that of infectious encephalitis. Methods We performed a population‐based …
compare it to that of infectious encephalitis. Methods We performed a population‐based …
Autoimmune encephalitis: clinical spectrum and management
Autoimmune encephalitis defines brain inflammation caused by a misdirected immune
response against self-antigens expressed in the central nervous system. It comprises a …
response against self-antigens expressed in the central nervous system. It comprises a …
Acute symptomatic seizures secondary to autoimmune encephalitis and autoimmune‐associated epilepsy: conceptual definitions
Seizures are a well‐recognized and often prominent manifestation of autoimmune
encephalitic syndromes. Progress in detection of pathogenic neural autoantibodies has led …
encephalitic syndromes. Progress in detection of pathogenic neural autoantibodies has led …
Seronegative autoimmune encephalitis: clinical characteristics and factors associated with outcomes
Seronegative autoimmune encephalitis is autoimmune encephalitis without any identifiable
pathogenic antibody. Although it is a major subtype of autoimmune encephalitis, many …
pathogenic antibody. Although it is a major subtype of autoimmune encephalitis, many …
LGI1 antibodies alter Kv1.1 and AMPA receptors changing synaptic excitability, plasticity and memory
M Petit-Pedrol, J Sell, J Planagumà, F Mannara… - Brain, 2018 - academic.oup.com
Abstract Leucine-rich glioma-inactivated 1 (LGI1) is a secreted neuronal protein that forms a
trans-synaptic complex that includes the presynaptic disintegrin and metalloproteinase …
trans-synaptic complex that includes the presynaptic disintegrin and metalloproteinase …
LGI1 antibody encephalitis: acute treatment comparisons and outcome
A Rodriguez, CJ Klein, E Sechi, E Alden… - Journal of Neurology …, 2022 - jnnp.bmj.com
Objective To compare acute treatment responses and long-term outcome in leucine-rich
glioma-inactivated 1 (LGI1) antibody encephalitis. Methods Retrospective case series of 118 …
glioma-inactivated 1 (LGI1) antibody encephalitis. Methods Retrospective case series of 118 …
Randomized placebo‐controlled trial of intravenous immunoglobulin in autoimmune LGI1/CASPR2 epilepsy
Objective Drug‐resistant seizures are common in patients with leucine‐rich, glioma‐
inactivated 1 (LGI1)‐IgG associated and contactin‐associated protein‐like 2 (CASPR2)‐IgG …
inactivated 1 (LGI1)‐IgG associated and contactin‐associated protein‐like 2 (CASPR2)‐IgG …
LGI1, CASPR2 and related antibodies: a molecular evolution of the phenotypes
Recent biochemical observations have helped redefine antigenic components within the
voltage-gated potassium channel (VGKC) complex. The related autoantibodies may be now …
voltage-gated potassium channel (VGKC) complex. The related autoantibodies may be now …