Targeted therapy for advanced thyroid cancer: kinase inhibitors and beyond

ME Cabanillas, M Ryder, C Jimenez - Endocrine reviews, 2019 - academic.oup.com
The treatment of advanced thyroid cancer has undergone rapid evolution in the last decade,
with multiple kinase inhibitor drug approvals for each subtype of thyroid cancer and a …

Mechanisms of receptor tyrosine kinase activation in cancer

Z Du, CM Lovly - Molecular cancer, 2018 - Springer
Receptor tyrosine kinases (RTKs) play an important role in a variety of cellular processes
including growth, motility, differentiation, and metabolism. As such, dysregulation of RTK …

2021 American thyroid association guidelines for management of patients with anaplastic thyroid cancer: American thyroid association anaplastic thyroid cancer …

KC Bible, E Kebebew, J Brierley, JP Brito… - Thyroid, 2021 - liebertpub.com
Background: Anaplastic thyroid cancer (ATC) is a rare but highly lethal form of thyroid
cancer. Since the guidelines for the management of ATC by the American Thyroid …

Anaplastic thyroid carcinoma: from clinicopathology to genetics and advanced therapies

E Molinaro, C Romei, A Biagini, E Sabini… - Nature Reviews …, 2017 - nature.com
Anaplastic thyroid carcinoma (ATC) is a rare malignancy, accounting for 1–2% of all thyroid
cancers. Although rare, ATC accounts for the majority of deaths from thyroid carcinoma. ATC …

Sorafenib in radioactive iodine-refractory, locally advanced or metastatic differentiated thyroid cancer: a randomised, double-blind, phase 3 trial

MS Brose, CM Nutting, B Jarzab, R Elisei, S Siena… - The Lancet, 2014 - thelancet.com
Background Patients with radioactive iodine (131 I)-refractory locally advanced or metastatic
differentiated thyroid cancer have a poor prognosis because of the absence of effective …

2015 American Thyroid Association management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer: the American Thyroid Association …

BR Haugen, EK Alexander, KC Bible, GM Doherty… - Thyroid, 2016 - liebertpub.com
Background: Thyroid nodules are a common clinical problem, and differentiated thyroid
cancer is becoming increasingly prevalent. Since the American Thyroid Association's …

[PDF][PDF] Guidelines for the management of thyroid cancer.

P Perros, K Boelaert, S Colley, C Evans… - Clinical …, 2014 - rouxgroup.org.uk
Guidelines for the management of thyroid cancer Page 1 CLINICAL ENDOCRINOLOGY
VOLUME 81 SUPPLEMENT 1 JULY 2014 THE CLINICAL JOURNAL OF THE SOCIETY FOR …

Molecular pathogenesis and mechanisms of thyroid cancer

M **ng - Nature Reviews Cancer, 2013 - nature.com
Thyroid cancer is a common endocrine malignancy. There has been exciting progress in
understanding its molecular pathogenesis in recent years, as best exemplified by the …

Revised American Thyroid Association management guidelines for patients with thyroid nodules and differentiated thyroid cancer: the American Thyroid Association …

DS Cooper, GM Doherty, BR Haugen, RT Kloos… - Thyroid, 2009 - liebertpub.com
Background: Thyroid nodules are a common clinical problem, and differentiated thyroid
cancer is becoming increasingly prevalent. Since the publication of the American Thyroid …

Vemurafenib Redifferentiation of BRAF Mutant, RAI-Refractory Thyroid Cancers

LA Dunn, EJ Sherman, SS Baxi… - The Journal of …, 2019 - academic.oup.com
Context BRAFV600E mutant thyroid cancers are often refractory to radioiodine (RAI).
Objectives To investigate the utility and molecular underpinnings of enhancing lesional …