The success of diffusion magnetic resonance imaging (MRI) is deeply rooted in the powerful
concept that during their random, diffusion‐driven displacements molecules probe tissue …

After more than 100 years of research, the neuropathology of schizophrenia remains
unknown and this is despite the fact that both: Kraepelin, E., 1919/1971. Dementia praecox …

We have developed a method for automated probabilistic reconstruction of a set of major
white-matter pathways from diffusion-weighted MR images. Our method is called TRACULA …

The disconnection hypothesis suggests that the core symptoms of schizophrenia (SZ) are
related to aberrant, or 'dys-', connectivity between distinct brain regions. A proliferation of …

While multiple theories have been put forth regarding the origin of schizophrenia, by far the
vast majority of evidence points to the neurodevelopmental model in which developmental …

Adolescent-onset schizophrenia provides an exceptional opportunity to explore the
neuropathology of schizophrenia free from the potential confounds of prolonged periods of …

Both post-mortem and neuroimaging studies have contributed significantly to what we know
about the brain and schizophrenia. MRI studies of volumetric reduction in several brain …

Magnetic resonance diffusion tensor imaging (DTI) is a non-invasive in vivo method for
characterizing the integrity of anatomical connections and white matter circuitry and provides …

In patients with schizophrenia neuroimaging studies have revealed global differences with
some brain regions showing focal abnormalities. Examining neurocircuitry, diffusion …

The ability to measure myelin in vivo has great consequences for furthering our knowledge
of normal development, as well as for understanding a wide range of neurological disorders …