Antiinflammatory, Antioxidant, and Immunomodulatory Effects of Crocus sativus L. and its Main Constituents

MH Boskabady, T Farkhondeh - Phytotherapy Research, 2016 - Wiley Online Library
Crocus sativus L.(C. sativus), commonly known as saffron, is used as a food additive,
preservative, and medicinal herb. Traditionally, it has been used as an alternative treatment …

The effects of toxic heavy metals lead, cadmium and copper on the epidemiology of male and female infertility

A Manouchehri, S Shokri, M Pirhadi… - JBRA assisted …, 2022 - pmc.ncbi.nlm.nih.gov
Infertility is a major problem in modern society that affects a significant number of couples
around the world. Heavy metals and a number of other factors have been causally linked to …

Relationships between seminal plasma metals/metalloids and semen quality, sperm apoptosis and DNA integrity

YX Wang, P Wang, W Feng, C Liu, P Yang… - Environmental …, 2017 - Elsevier
This study aimed to investigate the relationships between environmental exposure to
metals/metalloids and semen quality, sperm apoptosis and DNA integrity using the …

Protective role of curcumin in cadmium-induced testicular injury in mice by attenuating oxidative stress via Nrf2/ARE pathway

SH Yang, JB He, LH Yu, L Li, M Long, MD Liu… - … Science and Pollution …, 2019 - Springer
The aim of the present study was to investigate whether curcumin (CUR) can ameliorate
cadmium-induced reproductive toxicity and its mechanism. A total of 48 male mice were …

Saffron as an antidote or a protective agent against natural or chemical toxicities

BM Razavi, H Hosseinzadeh - DARU Journal of Pharmaceutical Sciences, 2015 - Springer
Saffron (Crocus sativus) is an extensively used food additive for its color and taste. Since
ancient times this plant has been introduced as a marvelous medicine throughout the world …

An evidence‐based approach to medicinal plants for the treatment of sperm abnormalities in traditional P ersian medicine

M Tahvilzadeh, M Hajimahmoodi, T Toliyat… - Andrologia, 2016 - Wiley Online Library
Infertility is defined as inability of a sexually active couple to conceive after 1 year of regular
intercourse without contraception. Male factors account for 20%–50% of cases of infertility …

Association of urinary metal levels with human semen quality: A cross-sectional study in China

YX Wang, Y Sun, W Feng, P Wang, P Yang, J Li… - Environment …, 2016 - Elsevier
Background Exposure to metals, including essential and nonessential elements, has been
linked to male reproductive health in animals. However, findings from human studies are …

Cadmium exposure and its association with oxidative stress, MT1A methylation, and idiopathic male infertility in Egypt: A case-control study

J Hassan, A Elmetwalli, M Helal, EA Al Munajer… - Food and Chemical …, 2024 - Elsevier
Idiopathic male infertility, a significant health concern, lacks a clear etiology. Cadmium (Cd),
a widespread environmental pollutant known to impact male reproductive health negatively …

Effect of crocin on biochemical parameters, oxidative/antioxidative profiles, sperm characteristics and testicular histopathology in streptozotocin-induced diabetic rats

SM Sefidgar, M Ahmadi-Hamedani… - Avicenna Journal of …, 2019 - pmc.ncbi.nlm.nih.gov
Objective: Chronic hyperglycemia and overproduction of reactive oxygen species (ROS) are
strong predictors of the development of reproductive complications of diabetes. The present …

Protective effect of crocin against d-galactose-induced aging in mice

E Mohammadi, S Mehri, HB Bostan… - Avicenna journal of …, 2018 - pmc.ncbi.nlm.nih.gov
Objective: Aging is a multifactorial phenomenon, which attribute to different diseases and
abnormalities in living systems. Oxidative stress, which is an important factor in aging …