Untangling the cortico-thalamo-cortical loop: cellular pieces of a knotty circuit puzzle

GMG Shepherd, N Yamawaki - Nature Reviews Neuroscience, 2021 - nature.com
Functions of the neocortex depend on its bidirectional communication with the thalamus, via
cortico-thalamo-cortical (CTC) loops. Recent work dissecting the synaptic connectivity in …

Excitatory neuronal connectivity in the barrel cortex

D Feldmeyer - Frontiers in neuroanatomy, 2012 - frontiersin.org
Neocortical areas are believed to be organized into vertical modules, the cortical columns,
and the horizontal layers 1–6. In the somatosensory barrel cortex these columns are defined …

A mesoscale connectome of the mouse brain

SW Oh, JA Harris, L Ng, B Winslow, N Cain, S Mihalas… - Nature, 2014 - nature.com
Comprehensive knowledge of the brain's wiring diagram is fundamental for understanding
how the nervous system processes information at both local and global scales. However …

Global and local fMRI signals driven by neurons defined optogenetically by type and wiring

JH Lee, R Durand, V Gradinaru, F Zhang, I Goshen… - Nature, 2010 - nature.com
Despite a rapidly-growing scientific and clinical brain imaging literature based on functional
magnetic resonance imaging (fMRI) using blood oxygenation level-dependent (BOLD) …

Anatomical pathways involved in generating and sensing rhythmic whisker movements

LWJ Bosman, AR Houweling, CB Owens… - Frontiers in integrative …, 2011 - frontiersin.org
The rodent whisker system is widely used as a model system for investigating sensorimotor
integration, neural mechanisms of complex cognitive tasks, neural development, and …

A role for the claustrum in salience processing?

JB Smith, GDR Watson, Z Liang, Y Liu… - Frontiers in …, 2019 - frontiersin.org
The claustrum (CLA) is a subcortical structure, present only in mammals, whose function
remains uncertain. Previously, using resting-state functional magnetic resonance imaging …

Thalamic neuromodulation and its implications for executive networks

C Varela - Frontiers in neural circuits, 2014 - frontiersin.org
The thalamus is a key structure that controls the routing of information in the brain.
Understanding modulation at the thalamic level is critical to understanding the flow of …

Comparative three-dimensional connectome map of motor cortical projections in the mouse brain

M Jeong, Y Kim, J Kim, DD Ferrante, PP Mitra… - Scientific reports, 2016 - nature.com
The motor cortex orchestrates simple to complex motor behaviors through its output
projections to target areas. The primary (MOp) and secondary (MOs) motor cortices are …

Sensory processing in the dorsolateral striatum: the contribution of thalamostriatal pathways

KD Alloway, JB Smith, TM Mowery… - Frontiers in systems …, 2017 - frontiersin.org
The dorsal striatum has two functionally-defined subdivisions: a dorsomedial striatum (DMS)
region involved in mediating goal-directed behaviors that require conscious effort, and a …

Functional specificity of claustrum connections in the rat: interhemispheric communication between specific parts of motor cortex

JB Smith, KD Alloway - Journal of Neuroscience, 2010 - Soc Neuroscience
Recent evidence indicates that the rat claustrum interconnects the motor cortical areas in
both hemispheres. To elucidate the functional specificity of the interhemispheric connections …