Traditional chemotherapy suffers from severe toxicity and side effects that limit its maximum
application in cancer therapy. To overcome this challenge, an ideal treatment strategy would …

Nanomedicine has been extensively explored to enhance the efficacy of chemotherapy with
modest therapeutic efficacy in the clinic, owing to various factors. A primary factor is …

Pharmaceutical drug therapy is often hindered by issues caused by poor drug selectivity,
including unwanted side effects and drug resistance. Spatial and temporal control over drug …

Colloidal gold has been studied for its potential application in medicine for centuries.
However, synthesis and evaluation of various gold nanoparticles have only recently been …

In comparison with 2D cell culture models, 3D spheroids are able to accurately mimic some
features of solid tumors, such as their spatial architecture, physiological responses …

Gold nanoparticles (AuNPs) have emerged as novel radiosensitizers owing to their high X-
ray absorption, synthetic versatility, and unique chemical, electronic and optical properties …

The design and use of materials in the nanoscale size range for addressing medical and
health-related issues continues to receive increasing interest. Research in nanomedicine …

A principal goal of cancer nanomedicine is to deliver therapeutics effectively to cancer cells
within solid tumors. However, there are a series of biological barriers that impede …

Gene therapy is a promising strategy for the treatment of monogenic disorders. Non-viral
gene delivery systems including lipid-based DNA therapeutics offer the opportunity to …

Cancer nanotherapeutics are progressing at a steady rate; research and development in the
field has experienced an exponential growth since early 2000's. The path to the …