Organ-on-a-chip (OOC) is an emerging technology that simulates an artificial organ within a
microfluidic cell culture chip. Current cell biology research focuses on in vitro cell cultures …

In the last decade, organoid research has entered a golden era, signifying a pivotal shift in
the biomedical landscape. The year 2023 marked a milestone with the publication of …

While the human gut microbiota has a significant impact on gut health and disease,
understanding of the roles of gut microbes, interactions, and collective impact of gut …

The continued rise in metabolic diseases such as obesity and type 2 diabetes mellitus poses
a global health burden, necessitating further research into factors implicated in the onset …

Bacterial communities are ubiquitous, found in natural ecosystems, such as soil, and within
living organisms, like the human microbiome. The dynamics of these communities in diverse …

The gut microbiome plays a major role in human health; however, little is known about the
structural arrangement of microbes and factors governing their distribution. In this work, we …

Introduction Recent years have witnessed remarkable progress in the development of cell-
based in vitro models aimed at predicting drug permeability, particularly focusing on …

The gut is a vital organ that is central to the absorption and metabolic processing of orally
administered drugs. While there have been many models developed with the goal of …

Bioengineered strategies enable gut chips to faithfully replicate essential features of
intestinal microsystems, encompassing geometric properties, peristalsis, intraluminal fluid …

As a booming engineering technology, the microfluidic chip has been widely applied for
replicating the complexity of human intestinal micro-physiological ecosystems in vitro …