The mitochondrial respiratory chain, also known as the electron transport chain (ETC), is
crucial to life, and energy production in the form of ATP is the main mitochondrial function …

Mitochondria are the power stations of the eukaryotic cell, using the energy released by the
oxidation of glucose and other sugars to produce ATP. Electrons are transferred from NADH …

Complex I is the first enzyme in the respiratory chain, which is responsible for energy
production in mitochondria and bacteria. Complex I couples the transfer of two electrons …

Complex I (NADH: ubiquinone oxidoreductase) is crucial for respiration in many aerobic
organisms. In mitochondria, it oxidizes NADH from the tricarboxylic acid cycle and β …

A substantial amount of mitochondrial energy is required for cell-cycle progression. The
mechanisms underlying the coordination of the mitochondrial respiration with cell-cycle …

Photosynthetic complex I enables cyclic electron flow around photosystem I, a regulatory
mechanism for photosynthetic energy conversion. We report a 3.3-angstrom-resolution cryo …

Complex I is one of the major respiratory complexes, conserved from bacteria to mammals. It
oxidises NADH, reduces quinone and pumps protons across the membrane, thus playing a …

A mammalian cell houses two genomes located separately in the nucleus and mitochondria.
During evolution, communications and adaptations between these two genomes occur …

The oxidative phosphorylation system is one of the best-characterized metabolic pathways.
In mammals, the protein components and X-ray structures are defined for all complexes …

Electrons have so little mass that in less than a second they can tunnel through potential
energy barriers that are several electron-volts high and several nanometers wide. Electron …