Alpha-1-acid glycoprotein

T Fournier, N Medjoubi-N, D Porquet - Biochimica et Biophysica Acta (BBA) …, 2000 - Elsevier
Alpha-1-acid glycoprotein (AGP) or orosomucoid (ORM) is a 41–43-kDa glycoprotein with a
pI of 2.8–3.8. The peptide moiety is a single chain of 183 amino acids (human) or 187 amino …

α1-Acid glycoprotein: an acute phase protein with inflammatory and immunomodulating properties

T Hochepied, FG Berger, H Baumann… - Cytokine & growth factor …, 2003 - Elsevier
α1-Acid glycoprotein (AGP) is a protein with a molecular weight of 41–43kDa and is heavily
glycosylated (45%). Due to the presence of sialic acids, it is negatively charged (pI= 2.7 …

Astrocytic orosomucoid-2 modulates microglial activation and neuroinflammation

M Jo, JH Kim, GJ Song, M Seo… - Journal of …, 2017 - Soc Neuroscience
Orosomucoid (ORM) is an acute-phase protein that belongs to the immunocalin subfamily, a
group of small-molecule-binding proteins with immunomodulatory functions. Little is known …

The acute phase protein α1-acid glycoprotein: a model for altered glycosylation during diseases

F Ceciliani, V Pocacqua - Current Protein and Peptide Science, 2007 - ingentaconnect.com
Glycosylation is one of the most important post-translational modifications of proteins, and
has been widely acknowledged as one of the most important ways to modulate both protein …

Immunocalins: a lipocalin subfamily that modulates immune and inflammatory responses

L Lögdberg, L Wester - Biochimica et Biophysica Acta (BBA)-Protein …, 2000 - Elsevier
A subset of the lipocalins, notably α1-acid glycoprotein, α1-microglobulin, and glycodelin,
exert significant immunomodulatory effects in vitro. Interestingly, all three are encoded from …

Glycosylation changes on serum glycoproteins in ovarian cancer may contribute to disease pathogenesis

R Saldova, MR Wormald, RA Dwek… - Disease …, 2008 - content.iospress.com
Glycosylation changes on serum glycoproteins in ovarian cancer may contribute to disease
pathogenesis Page 1 Disease Markers 25 (2008) 219–232 219 IOS Press Glycosylation …

The immune functions of α1 acid glycoprotein

F Ceciliani, C Lecchi - Current Protein and Peptide Science, 2019 - ingentaconnect.com
α1-acid glycoprotein (orosomucoid, AGP) is an Acute Phase Protein produced by liver and
peripheral tissues in response to systemic reaction to inflammation. AGP functions have …

Inflammation-induced expression of sialyl Lewis X-containing glycan structures on alpha 1-acid glycoprotein (orosomucoid) in human sera.

TW De Graaf, ME Van der Stelt, MG Anbergen… - The Journal of …, 1993 - rupress.org
The glycosylation of the acute phase glycoprotein alpha 1-acid glycoprotein (AGP) in human
sera is subject to marked changes during acute inflammation as a result of the cytokine …

Analysis of the five glycosylation sites of human α1-acid glycoprotein

MJ Treuheit, CE Costello, HB Halsall - Biochemical Journal, 1992 - portlandpress.com
Orosomucoid (OMD) contains complex bi-, tri-and tetra-antennary glycan chains.
Subfractionation of OMD into three molecular variants using concanavalin A lectin …

α1-Acid glycoprotein (orosomucoid): pathophysiological changes in glycosylation in relation to its function

W Van Dijk, EC Havenaar… - Glycoconjugate …, 1995 - Springer
The aim of this review is to summarize the research efforts of the last two decades with
respect to (i) the determination and characterization of the changes in glycosylation of AGP …