[HTML][HTML] Epigenetics, microRNA and metabolic syndrome: a comprehensive review

F Ramzan, MH Vickers, RF Mithen - International Journal of Molecular …, 2021 - mdpi.com
Epigenetics refers to the DNA chemistry changes that result in the modification of gene
transcription and translation independently of the underlying DNA coding sequence …

Childhood obesity, metabolic syndrome, and oxidative stress: microRNAs go on stage

Á González-Domínguez, T Belmonte… - Reviews in Endocrine …, 2023 - Springer
The incidence of childhood obesity and metabolic syndrome has grown notably in the last
years, becoming major public health burdens in developed countries. Nowadays, oxidative …

MicroRNAs and other non-coding RNAs in adipose tissue and obesity: emerging roles as biomarkers and therapeutic targets

S Lorente-Cebrián, P González-Muniesa… - Clinical …, 2019 - portlandpress.com
Obesity is a metabolic condition usually accompanied by insulin resistance (IR), type 2
diabetes (T2D), and dyslipidaemia, which is characterised by excessive fat accumulation …

Epigenetics, obesity and early-life cadmium or lead exposure

SS Park, DA Skaar, RL Jirtle, C Hoyo - Epigenomics, 2017 - Taylor & Francis
Obesity is a complex and multifactorial disease, which likely comprises multiple subtypes.
Emerging data have linked chemical exposures to obesity. As organismal response to …

Perspectives and challenges of epigenetic determinants of childhood obesity: a systematic review

R Alfano, O Robinson, E Handakas, TS Nawrot… - Obesity …, 2022 - Wiley Online Library
The tremendous increase in childhood obesity prevalence over the last few decades cannot
merely be explained by genetics and evolutionary changes in the genome, implying that …

A new insight into the roles of MiRNAs in metabolic syndrome

Y Huang, Y Yan, W Xv, G Qian, C Li… - BioMed research …, 2018 - Wiley Online Library
Metabolic syndrome (MetS), which includes several clinical components such as abdominal
obesity, insulin resistance (IR), dyslipidemia, microalbuminuria, hypertension …

Circadian gene methylation profiles are associated with obesity, metabolic disturbances and carbohydrate intake

O Ramos-Lopez, M Samblas, FI Milagro… - Chronobiology …, 2018 - Taylor & Francis
The circadian clock regulates the daily rhythms of several physiological and behavioral
processes. Disruptions in clock genes have been associated with obesity and related …

Circulating miRNAs in girls with abdominal obesity: miR‐221‐3p as a biomarker of response to weight loss interventions

A Ojeda‐Rodríguez, TS Assmann… - Pediatric …, 2022 - Wiley Online Library
Background Recent studies have associated several microRNAs (miRNAs) with childhood
obesity and energy homeostasis, suggesting that an individual miRNA profile could be used …

A randomized controlled trial for overweight and obesity in preschoolers: the More and Less Europe study-an intervention within the STOP project

A Ek, C Delisle Nyström, A Chirita-Emandi, JA Tur… - BMC Public Health, 2019 - Springer
Background Childhood overweight and obesity is a serious public health issue with an
increase being observed in preschool-aged children. Treating childhood obesity is difficult …