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NAD+ metabolism: pathophysiologic mechanisms and therapeutic potential
Nicotinamide adenine dinucleotide (NAD+) and its metabolites function as critical regulators
to maintain physiologic processes, enabling the plastic cells to adapt to environmental …
to maintain physiologic processes, enabling the plastic cells to adapt to environmental …
The microbiota-gut-brain axis
I. INTRODUCTION 1877 II. STUDYING THE... 1881 III. MICROBIOTA-GUT-BRAIN AXIS...
1907 IV. PATHWAYS OF COMMUNICATION 1911 V. MICROBIOTA AND SYNAPTIC... 1929 …
1907 IV. PATHWAYS OF COMMUNICATION 1911 V. MICROBIOTA AND SYNAPTIC... 1929 …
Human monocyte subsets and phenotypes in major chronic inflammatory diseases
Human monocytes are divided in three major populations; classical (CD14+ CD16−), non-
classical (CD14dimCD16+), and intermediate (CD14+ CD16+). Each of these subsets is …
classical (CD14dimCD16+), and intermediate (CD14+ CD16+). Each of these subsets is …
Huntington disease: new insights into molecular pathogenesis and therapeutic opportunities
Huntington disease (HD) is a neurodegenerative disease caused by CAG repeat expansion
in the huntingtin gene (HTT) and involves a complex web of pathogenic mechanisms …
in the huntingtin gene (HTT) and involves a complex web of pathogenic mechanisms …
[HTML][HTML] Mitochondria and brain disease: a comprehensive review of pathological mechanisms and therapeutic opportunities
Mitochondria play a vital role in maintaining cellular energy homeostasis, regulating
apoptosis, and controlling redox signaling. Dysfunction of mitochondria has been implicated …
apoptosis, and controlling redox signaling. Dysfunction of mitochondria has been implicated …
Structural variant calling: the long and the short of it
Recent research into structural variants (SVs) has established their importance to medicine
and molecular biology, elucidating their role in various diseases, regulation of gene …
and molecular biology, elucidating their role in various diseases, regulation of gene …
Neurogenesis in aging and age-related neurodegenerative diseases
Adult neurogenesis, the process by which neurons are generated in certain areas of the
adult brain, declines in an age-dependent manner and is one potential target for extending …
adult brain, declines in an age-dependent manner and is one potential target for extending …
The application of ferroptosis in diseases
Ferroptosis is a new kind of regulated cell death that is characterized by highly iron-
dependent lipid peroxidation. Ferroptosis involves various biology processes, such as iron …
dependent lipid peroxidation. Ferroptosis involves various biology processes, such as iron …
New insights into oxidative stress and inflammatory response in neurodegenerative diseases
E Scarian, C Viola, F Dragoni, R Di Gerlando… - International Journal of …, 2024 - mdpi.com
Oxidative stress (OS) and inflammation are two important and well-studied pathological
hallmarks of neurodegenerative diseases (NDDs). Due to elevated oxygen consumption, the …
hallmarks of neurodegenerative diseases (NDDs). Due to elevated oxygen consumption, the …
The role of microRNAs in neurodegenerative diseases: a review
MicroRNAs (miRNAs) are non-coding RNAs which are essential post-transcriptional gene
regulators in various neuronal degenerative diseases and playact a key role in these …
regulators in various neuronal degenerative diseases and playact a key role in these …