Praziquantel: An update on the mechanism of its action against schistosomiasis and new therapeutic perspectives

RA Nogueira, MGS Lira, ICL Licá, GCCG Frazão… - Molecular and …, 2022 - Elsevier
Praziquantel (PZQ) is the drug of choice for the treatment of all forms of schistosomiasis,
although its mechanisms of action are not completely understood. PZQ acts largely on adult …

Human schistosomiasis in Nigeria: present status, diagnosis, chemotherapy, and herbal medicines

U Saidu, MA Ibrahim, HP de Koning, JH McKerrow… - Parasitology …, 2023 - Springer
Schistosomiasis is a neglected tropical disease caused by a parasitic, trematode blood fluke
of the genus Schistosoma. With 20 million people infected, mostly due to Schistosoma …

Alternatives to praziquantel for the prevention and control of schistosomiasis

T Spangenberg - ACS Infectious Diseases, 2020 - ACS Publications
Schistosomiasis, a neglected tropical disease provoked by infection with parasitic blood
flukes of the genus Schistosoma, affects almost 240 million people worldwide, and more …

Schistosomiasis and hookworm infection in humans: Disease burden, pathobiology and anthelmintic vaccines

N Tsuji - Parasitology international, 2020 - Elsevier
Helminth diseases are the ancient scourges of humans and their damages are 'silent and
insidious'. Of the helminth infections, schistosomiasis and hookworm infection have a great …

[HTML][HTML] Ascaridia galli, a common nematode in semiscavenging indigenous chickens in Bangladesh: epidemiology, genetic diversity, pathobiology, ex vivo culture …

SN Ritu, SS Labony, MS Hossain, MH Ali, MM Hasan… - Poultry Science, 2024 - Elsevier
Ascaridia galli is the most common nematode in chickens. Ascaridia galli is highly prevalent
in chickens reared in scavenging or semiscavenging systems. Here, we studied the …

Recent advances in the development of adenovirus-vectored vaccines for parasitic infections

C Koger-Pease, DJ Perera, M Ndao - Pharmaceuticals, 2023 - mdpi.com
Vaccines against parasites have lagged centuries behind those against viral and bacterial
infections, despite the devastating morbidity and widespread effects of parasitic diseases …

A cercarial invadolysin interferes with the host immune response and facilitates infection establishment of Schistosoma mansoni

JR Hambrook, PC Hanington - PLoS pathogens, 2023 - journals.plos.org
Schistosoma mansoni employs immune evasion and immunosuppression to overcome
immune responses mounted by its snail and human hosts. Myriad immunomodulating …

Helminth egg derivatives as proregenerative immunotherapies

DR Maestas Jr, L Chung, J Han, X Wang… - Proceedings of the …, 2023 - pnas.org
The immune system is increasingly recognized as an important regulator of tissue repair. We
developed a regenerative immunotherapy from the helminth Schistosoma mansoni soluble …

Zoonotic human liver flukes, a type 1 biocarcinogen, in freshwater fishes: genetic analysis and confirmation of molluscan vectors and reservoir hosts in Bangladesh

SS Labony, MA Alim, MM Hasan… - Infectious Diseases of …, 2024 - mednexus.org
Background Opisthorchiid flukes, particularly Opisthorchis viverrini, Opisthorchis felineus,
Clonorchis sinensis, and Metorchis spp. are the most common fish-borne zoonotic human …

Prevalence of urinary schistosomiasis in women: a systematic review and meta-analysis of recently published literature (2016–2020)

M Shams, S Khazaei, E Ghasemi, N Nazari… - Tropical Medicine and …, 2022 - Springer
Background Urinary schistosomiasis is a serious threat in endemic territories of Africa and
the Middle East. The status of female urinary schistosomiasis (FUS) in published literature …