β-Carboline alkaloids are a large group of natural and synthetic indole alkaloids with
different degrees of aromaticity, some of which are widely distributed in nature, including …

Harmine, a beta-carboline alkaloid, is widely distributed in the plants, marine creatures,
insects, mammalians as well as in human tissues and body fluids. Harmine was originally …

The specificities of 65 compounds reported to be relatively specific inhibitors of protein
kinases have been profiled against a panel of 70–80 protein kinases. On the basis of this …

Peganum harmala L. is a multipurpose medicinal plant increasingly used for psychoactive
recreational purposes (Ayahuasca analog). Harmaline, harmine, harmalol, harmol and …

Harmine is isolated from the seeds of the medicinal plant, Peganum harmala L., and has
been used for thousands of years in the Middle East and China. Harmine has many …

DYRK1A is a dual‐specificity protein kinase that autophosphorylates a conserved tyrosine
residue in the activation loop but phosphorylates exogenous substrates only at serine or …

The natural β-carboline alkaloids display similarities with neurotransmitters that can be
favorably exploited to design bioactive and bioavailable drugs for Alzheimer's disease (AD) …

Abstract β-Carboline alkaloids are a family of natural and synthetic products with structural
diversity and outstanding antitumor activities. This review summarizes research …

Spinal-Z, a methanolic mixture of dried powdered seeds of Peganum harmala Linn. and leaf
of Dracocephalum kotschyii Boiss. is an Iranian ethno-medical remedy. It has been used for …

PPARγ is the master regulator of adipogenesis and the molecular target of the
thiazolidinedione antidiabetic drugs. By screening for compounds that promote …