Butyrylcholinesterase for protection from organophosphorus poisons: catalytic complexities and hysteretic behavior

P Masson, O Lockridge - Archives of biochemistry and biophysics, 2010 - Elsevier
Butyrylcholinesterase is a promiscuous enzyme that displays complex kinetic behavior. It is
toxicologically important because it detoxifies organophosphorus poisons (OP) by making a …

Immunotoxic role of organophosphates: An unseen risk escalating SARS-CoV-2 pathogenicity

P Rajak, A Ganguly, S Sarkar, M Mandi, M Dutta… - Food and Chemical …, 2021 - Elsevier
Consistent gathering of immunotoxic substances on earth is a serious global issue affecting
people under pathogenic stress. Organophosphates are among such hazardous …

[HTML][HTML] In Vitro Anti-Cholinesterase and Antioxidant Activity of Extracts of Moringa oleifera Plants from Rivers State, Niger Delta, Nigeria

LL Nwidu, E Elmorsy, JS Aprioku, I Siminialayi… - Medicines, 2018 - mdpi.com
This study evaluated Moringa oleifera extracts from two locations in Niger Delta for in vitro
anti-cholinesterase and antioxidant activities. Methanolic, aqueous and ethanolic extracts of …

Potential nutraceutical properties of leaves from several commonly cultivated plants

H Amat-ur-Rasool, F Symes, D Tooth, LN Schaffert… - Biomolecules, 2020 - mdpi.com
Chronic dietary ingestion of suitable phytochemicals may assist with limiting or negating
neurodegenerative decline. Current therapeutics used to treat Alzheimer disease elicit …

[HTML][HTML] An investigation of the neurotoxic effects of malathion, chlorpyrifos, and paraquat to different brain regions

E Elmorsy, A Al-Ghafari, H Al Doghaither, M Salama… - Brain sciences, 2022 - mdpi.com
Acute or chronic exposures to pesticides have been linked to neurotoxicity and the potential
development of neurodegenerative diseases (NDDs). This study aimed to consider the …

The protective effect of Indian Catechu methanolic extract against aluminum chloride-induced neurotoxicity, A rodent model of Alzheimer's disease

E Elmorsy, E Elsharkawy, FA Alhumaydhi, M Salama - Heliyon, 2021 - cell.com
Alzheimer's disease (AD) is the commonest neurodegenerative disorder with a wide array of
manifestations, courses, and contributing causes. Despite being clinically characterized a …

[HTML][HTML] A Preliminary Assessment of the Nutraceutical Potential of Acai Berry (Euterpe sp.) as a Potential Natural Treatment for Alzheimer's Disease

MN ALNasser, IR Mellor, WG Carter - Molecules, 2022 - mdpi.com
Alzheimer's disease (AD) is characterised by progressive neuronal atrophy and the loss of
neuronal function as a consequence of multiple pathomechanisms. Current AD treatments …

Anti-acetylcholinesterase activity and antioxidant properties of extracts and fractions of Carpolobia lutea

LL Nwidu, E Elmorsy, J Thornton… - Pharmaceutical …, 2017 - Taylor & Francis
Context: There is an unmet need to discover new treatments for Alzheimer's disease. This
study determined the anti-acetylcholinesterase (AChE) activity, DPPH free radical …

Organophosphorus pesticide exposure biomarkers in a Mexican population

JF Herrera-Moreno, IM Medina-Díaz… - … Science and Pollution …, 2021 - Springer
The organophosphate (OP) pesticides are neurotoxic compounds widely used around the
world. Evaluation of OP exposure in human studies is important for enabling adequate data …

Differentiated Neurons Are More Vulnerable to Organophosphate and Carbamate Neurotoxicity than Undifferentiated Neurons Due to the Induction of Redox Stress …

AW Mudyanselage, BC Wijamunige, A Kocon… - Brain Sciences, 2023 - mdpi.com
Organophosphate (OP) and carbamate pesticides are toxic to pests through targeted
inhibition of acetylcholinesterase (AChE). However, OPs and carbamates may be harmful to …