The tissue engineering field has developed in response to the shortcomings related to the
replacement of the tissues lost to disease or trauma: donor tissue rejection, chronic …

Advances in cell culture methods, multidisciplinary research, clinical need to replace lost
skin tissues and regulatory need to replace animal models with alternative test methods has …

Cutaneous tissue repair aims at restoring the barrier function of the skin. To achieve this,
defects need to be replaced by granulation tissue to form new connective tissue, and …

Three dimensional (3D) tissue models of the human skin are probably the most developed
and understood in vitro engineered constructs. The motivation to accomplish organotypic …

Skin wound healing is essential to health and survival. Consequently, high amounts of
research effort have been put into investigating the cellular and molecular components …

Atopic dermatitis (AD) is one of the most prevalent inflammatory disease among non-fatal
skin diseases, affecting up to one fifth of the population in developed countries. AD is …

Skin regeneration through tissue engineering combines biomaterials compatible with living
cells to build a niche of limited duration that can support recapitulating reconstruction of the …

Dermal wounds, both acute and chronic, represent a significant clinical challenge, and
therefore the development of novel biomaterial-based skin substitutes to promote skin repair …

Burn wound infections are often difficult to treat due to the presence of multidrug-resistant
bacterial strains and biofilms. Currently, mupirocin is used to eradicate methicillin-resistant …

Type 2 diabetes mellitus is a metabolic noncommunicable disease with an expanding
pandemic magnitude. Diabetes predisposes to lower extremities ulceration and impairs the …