Immune response in COVID-19: what is next?

Q Li, Y Wang, Q Sun, J Knopf, M Herrmann… - Cell Death & …, 2022 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) has been a global pandemic for more
than 2 years and it still impacts our daily lifestyle and quality in unprecedented ways. A …

Physiological roles of hydrogen sulfide in mammalian cells, tissues, and organs

G Cirino, C Szabo… - Physiological …, 2023 - journals.physiology.org
Over the last two decades, hydrogen sulfide (H2S) has emerged as an endogenous
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …

Chemical Biology of H2S Signaling through Persulfidation

MR Filipovic, J Zivanovic, B Alvarez… - Chemical …, 2018 - ACS Publications
Signaling by H2S is proposed to occur via persulfidation, a posttranslational modification of
cysteine residues (RSH) to persulfides (RSSH). Persulfidation provides a framework for …

Metabolic adaptation and maladaptation in adipose tissue

ET Chouchani, S Kajimura - Nature metabolism, 2019 - nature.com
Adipose tissue possesses the remarkable capacity to control its size and function in
response to a variety of internal and external cues, such as nutritional status and …

International union of basic and clinical pharmacology. CII: pharmacological modulation of H2S levels: H2S donors and H2S biosynthesis inhibitors

C Szabo, A Papapetropoulos, EH Ohlstein - Pharmacological reviews, 2017 - Elsevier
Over the last decade, hydrogen sulfide (H 2 S) has emerged as an important endogenous
gasotransmitter in mammalian cells and tissues. Similar to the previously characterized …

Emerging chemical biology of protein persulfidation

T Vignane, MR Filipovic - Antioxidants & Redox Signaling, 2023 - liebertpub.com
Significance: Protein persulfidation (the formation of RSSH), an evolutionarily conserved
oxidative posttranslational modification in which thiol groups in cysteine residues are …

MPST sulfurtransferase maintains mitochondrial protein import and cellular bioenergetics to attenuate obesity

A Katsouda, D Valakos, VS Dionellis, SI Bibli… - Journal of Experimental …, 2022 - rupress.org
Given the clinical, economic, and societal impact of obesity, unraveling the mechanisms of
adipose tissue expansion remains of fundamental significance. We previously showed that …

Homeostatic impact of sulfite and hydrogen sulfide on cysteine catabolism

JB Kohl, AT Mellis, G Schwarz - British journal of pharmacology, 2019 - Wiley Online Library
Cysteine is one of the two key sulfur‐containing amino acids with important functions in
redox homeostasis, protein functionality and metabolism. Cysteine is taken up by mammals …

[HTML][HTML] Unraveling the role of thiosulfate sulfurtransferase in metabolic diseases

PD Kruithof, S Lunev, SPA Lozano… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Abstract Thiosulfate sulfurtransferase (TST, EC 2.8. 1.1), also known as Rhodanese, is a
mitochondrial enzyme which catalyzes the transfer of sulfur in several molecular pathways …

Iron and sulfur oxidation pathways of Acidithiobacillus ferrooxidans

Y Zhan, M Yang, S Zhang, D Zhao, J Duan… - World Journal of …, 2019 - Springer
Acidithiobacillus ferrooxidans is a gram-negative, autotrophic and rod-shaped bacterium. It
can gain energy through the oxidation of Fe (II) and reduced inorganic sulfur compounds for …