The orbitofrontal cortex: a goal-directed cognitive map framework for social and non-social behaviors

W Shi, OC Meisner, S Blackmore, MP Jadi… - … of Learning and …, 2023 - Elsevier
The orbitofrontal cortex (OFC) is regarded as one of the core brain areas in a variety of value-
based behaviors. Over the past two decades, tremendous knowledge about the OFC …

[HTML][HTML] Microglia maintain structural integrity during fetal brain morphogenesis

AR Lawrence, A Canzi, C Bridlance, N Olivié… - Cell, 2024 - cell.com
Summary Microglia (MG), the brain-resident macrophages, play major roles in health and
disease via a diversity of cellular states. While embryonic MG display a large heterogeneity …

Biological determinants of the origin and development of the opposite psychological and behavioral traits associated with autism spectrum disorders and Williams …

K Vernerova, R Solc - Research in Autism Spectrum Disorders, 2024 - Elsevier
Williams syndrome is a genetical disorder caused by microdeletion on chromosome 7,
specifically of 7q11. 23 region. Its phenotype is characterized by typical facial features, mild …

Alterations in hippocampus-centered morphological features and function of the progression from normal cognition to mild cognitive impairment

X Wang, L Peng, S Zhan, X Yin, L Huang… - Asian Journal of …, 2024 - Elsevier
Mild cognitive impairment (MCI) is a significant precursor to dementia, highlighting the
critical need for early identification of individuals at high risk of MCI to prevent cognitive …

Increased functional connectivity between brain regions involved in social cognition, emotion and affective-value in psychedelic states induced by N, N …

C Soares, G Lima, ML Pais, M Teixeira… - Frontiers in …, 2024 - frontiersin.org
The modulation of social cognition is suggested as a possible mechanism contributing to the
potential clinical efficacy of psychedelics in disorders involving socio-emotional and reward …

Research progress on hippocampal neurogenesis in autism spectrum disorder

M Chen, L Guo, Q Li, S Yang, W Li, Y Lai… - Pediatric …, 2024 - Wiley Online Library
Autism spectrum disorder (ASD) is a group of severe neurodevelopmental disorders with
unclear etiology and significant heterogeneity that is emerging as a global public health …

[HTML][HTML] Early-in-life isoflurane exposure alters resting-state functional connectivity in juvenile non-human primates

V Neudecker, JF Perez-Zoghbi… - British journal of …, 2023 - Elsevier
Background Clinical studies suggest that anaesthesia exposure early in life affects
neurobehavioural development. We designed a non-human primate (NHP) study to …

[HTML][HTML] Mechanistic insights into retinoic-acid treatment for autism in the improvement of social behavior: Evidence from a multi omics study in rats

J Zhu, H Liu, Y Hu, J Liu, C Dai, J Liang, B Cheng… - …, 2025 - Elsevier
Background Autism spectrum disorder (ASD) is a lifelong condition. It is characterized by
complex etiologies, including disruptions in exogenous retinoic acid (RA) signaling, which …

Brain functional gradient and structure features in adolescent and adult autism spectrum disorders

L Ruan, G Chen, M Yao, C Li, X Chen… - Human Brain …, 2024 - Wiley Online Library
Understanding how function and structure are organized and their coupling with clinical
traits in individuals with autism spectrum disorder (ASD) is a primary goal in network …

Depression in adolescence and young adulthood: the difficulty to integrate motivational/emotional systems

T Giacolini, A Alcaro, D Conversi, L Tarsitani - Frontiers in Psychology, 2025 - frontiersin.org
Depression is presented as a multi-factorial bio-psycho-social expression that has evolved
primarily as an effect of stressors related to the motivational/emotional systems that regulate …