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Antimicrobial peptides immune modulation role in intracellular bacterial infection
Intracellular bacteria cause a wide range of diseases, and their intracellular lifestyle makes
infections difficult to resolve. Furthermore, standard therapy antibiotics are often unable to …
infections difficult to resolve. Furthermore, standard therapy antibiotics are often unable to …
[HTML][HTML] CXCL10 chemokine: a critical player in RNA and DNA viral infections
Chemokines constitute a group of small, secreted proteins that regulate leukocyte migration
and contribute to their activation. Chemokines are crucial inflammatory mediators that play a …
and contribute to their activation. Chemokines are crucial inflammatory mediators that play a …
Antimicrobial activity of mesenchymal stem cells: current status and new perspectives of antimicrobial peptide-based therapies
While mesenchymal stem cells (MSCs)-based therapy appears to be promising, there are
concerns regarding possible side effects related to the unwanted suppression of …
concerns regarding possible side effects related to the unwanted suppression of …
Antimicrobial peptides: pore formers or metabolic inhibitors in bacteria?
Antimicrobial peptides are an abundant and diverse group of molecules that are produced
by many tissues and cell types in a variety of invertebrate, plant and animal species. Their …
by many tissues and cell types in a variety of invertebrate, plant and animal species. Their …
The commensal skin microbiota triggers type I IFN–dependent innate repair responses in injured skin
J Di Domizio, C Belkhodja, P Chenuet, A Fries… - Nature …, 2020 - nature.com
Skin wounds heal by coordinated induction of inflammation and tissue repair, but the
initiating events are poorly defined. Here we uncover a fundamental role of commensal skin …
initiating events are poorly defined. Here we uncover a fundamental role of commensal skin …
Mechanisms of antimicrobial peptide action and resistance
MR Yeaman, NY Yount - Pharmacological reviews, 2003 - Elsevier
Antimicrobial peptides have been isolated and characterized from tissues and organisms
representing virtually every kingdom and phylum, ranging from prokaryotes to humans. Yet …
representing virtually every kingdom and phylum, ranging from prokaryotes to humans. Yet …
Platelet α-granules: Basic biology and clinical correlates
α-Granules are essential to normal platelet activity. These unusual secretory granules derive
their cargo from both regulated secretory and endocytotic pathways in megakaryocytes …
their cargo from both regulated secretory and endocytotic pathways in megakaryocytes …
Platelets in inflammation and infection
Although platelets are traditionally recognized for their central role in hemostasis, many lines
of research clearly demonstrate these rather ubiquitous blood components are potent …
of research clearly demonstrate these rather ubiquitous blood components are potent …
Risk of candidiasis associated with interleukin-17 inhibitors: A real-world observational study of multiple independent sources
L Davidson, JMPA van den Reek, M Bruno… - The Lancet Regional …, 2022 - thelancet.com
Background Biologics directed against the T-helper (Th)-17 pathway have been approved
for several inflammatory diseases. Interleukin (IL)-17 is involved in anti-Candida host …
for several inflammatory diseases. Interleukin (IL)-17 is involved in anti-Candida host …
[HTML][HTML] Lung epithelial cells: therapeutically inducible effectors of antimicrobial defense
Lung epithelial cells are increasingly recognized to be active effectors of microbial defense,
contributing to both innate and adaptive immune function in the lower respiratory tract. As …
contributing to both innate and adaptive immune function in the lower respiratory tract. As …