Stochastic approaches in systems biology

M Ullah, O Wolkenhauer - Wiley Interdisciplinary Reviews …, 2010 - Wiley Online Library
The discrete and random occurrence of chemical reactions far from thermodynamic
equilibrium, and low copy numbers of chemical species, in systems biology necessitate …

The stochastic dynamics of filopodial growth

Y Lan, GA Papoian - Biophysical journal, 2008 - cell.com
A filopodium is a cytoplasmic projection, exquisitely built and regulated, which extends from
the leading edge of the migrating cell, exploring the cell's neighborhood. Commonly …

[BOOK][B] Stochastic approaches for systems biology

M Ullah, O Wolkenhauer - 2011 - books.google.com
This textbook focuses on stochastic analysis in systems biology containing both the theory
and application. While the authors provide a review of probability and random variables …

Spectral solutions to stochastic models of gene expression with bursts and regulation

A Mugler, AM Walczak, CH Wiggins - … E—Statistical, Nonlinear, and Soft Matter …, 2009 - APS
Signal-processing molecules inside cells are often present at low copy number, which
necessitates probabilistic models to account for intrinsic noise. Probability distributions have …

Tfh exosomes derived from allergic rhinitis promote DC maturation through miR-142-5p/CDK5/STAT3 pathway

ZX Teng, XC Zhou, RT Xu, FY Zhu, X Bing… - Journal of …, 2022 - Taylor & Francis
Background Dendritic cells (DCs) play an important role in allergen signal presentation.
Many studies showed that follicular helper T cells (Tfhs) are related to allergic rhinitis (AR) …

Molecular noise of cap** protein binding induces macroscopic instability in filopodial dynamics

PI Zhuravlev, GA Papoian - Proceedings of the National …, 2009 - National Acad Sciences
Cap** proteins are among the most important regulatory proteins involved in controlling
complicated stochastic dynamics of filopodia, which are dynamic finger-like protrusions used …

A modified variational approach to noisy cell signaling

R Cai, Y Lan - The Journal of Chemical Physics, 2024 - pubs.aip.org
Signaling in cells is full of noise and, hence, described with stochastic biochemical models.
Thus, an efficient computation algorithm for these fluctuating reactions is much needed …

A stochastic spectral analysis of transcriptional regulatory cascades

AM Walczak, A Mugler… - Proceedings of the …, 2009 - National Acad Sciences
The past decade has seen great advances in our understanding of the role of noise in gene
regulation and the physical limits to signaling in biological networks. Here, we introduce the …

Mechano-chemical feedbacks regulate actin mesh growth in lamellipodial protrusions

L Hu, GA Papoian - Biophysical journal, 2010 - cell.com
During cell motion on a substratum, eukaryotic cells project sheetlike lamellipodia which
contain a dynamically remodeling three-dimensional actin mesh. A number of regulatory …

A critical quantity for noise attenuation in feedback systems

L Wang, J **n, Q Nie - PLoS Computational Biology, 2010 - journals.plos.org
Feedback modules, which appear ubiquitously in biological regulations, are often subject to
disturbances from the input, leading to fluctuations in the output. Thus, the question …