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Application of proteomics in cancer: recent trends and approaches for biomarkers discovery
YW Kwon, HS Jo, S Bae, Y Seo, P Song, M Song… - Frontiers in …, 2021 - frontiersin.org
Proteomics has become an important field in molecular sciences, as it provides valuable
information on the identity, expression levels, and modification of proteins. For example …
information on the identity, expression levels, and modification of proteins. For example …
Epidemiology and outcome of glioblastoma
Glioblastoma (GBM) is the most aggressive malignant primary brain tumor. With an
incidence rate of 3.19 per 100,000 persons in the United States and a median age of 64 …
incidence rate of 3.19 per 100,000 persons in the United States and a median age of 64 …
Time-resolved single-cell transcriptomics defines immune trajectories in glioblastoma
D Kirschenbaum, K ** of human glioblastoma reveals an invariant stem cell hierarchy
Human glioblastomas harbour a subpopulation of glioblastoma stem cells that drive
tumorigenesis. However, the origin of intratumoural functional heterogeneity between …
tumorigenesis. However, the origin of intratumoural functional heterogeneity between …
A feedforward mechanism mediated by mechanosensitive ion channel PIEZO1 and tissue mechanics promotes glioma aggression
Alteration of tissue mechanical properties is a physical hallmark of solid tumors including
gliomas. How tumor cells sense and regulate tissue mechanics is largely unknown. Here …
gliomas. How tumor cells sense and regulate tissue mechanics is largely unknown. Here …
EZH2 is a potential therapeutic target for H3K27M-mutant pediatric gliomas
Diffuse intrinsic pontine glioma (DIPG) is an aggressive brain tumor that is located in the
pons and primarily affects children. Nearly 80% of DIPGs harbor mutations in histone H3 …
pons and primarily affects children. Nearly 80% of DIPGs harbor mutations in histone H3 …