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Triple negative breast cancer: molecular subtype-specific immune landscapes with therapeutic implications
A Syrnioti, S Petousis, LA Newman… - Cancers, 2024 - mdpi.com
Simple Summary Triple Negative Breast Cancer (TNBC) comprises approximately 15–20%
of all breast cancer (BC) cases, is often diagnosed at an advanced stage, and is generally …
of all breast cancer (BC) cases, is often diagnosed at an advanced stage, and is generally …
[HTML][HTML] Navigating the immune maze: pioneering strategies for unshackling cancer immunotherapy resistance
Simple Summary Cancer treatments have made remarkable advances with the introduction
of immunotherapy, which recruits the body's immune system to fight cancer. Despite these …
of immunotherapy, which recruits the body's immune system to fight cancer. Despite these …
MDSCs in bone metastasis: mechanisms and therapeutic potential1
Z Li, Q **a, Y He, L Li, P Yin - Cancer Letters, 2024 - Elsevier
Bone metastasis (BM) is a frequent complication associated with advanced cancer that
significantly increases patient mortality. Myeloid-derived suppressor cells (MDSCs) play a …
significantly increases patient mortality. Myeloid-derived suppressor cells (MDSCs) play a …
[HTML][HTML] Mannan-Decorated Lipid Calcium Phosphate Nanoparticle Vaccine Increased the Antitumor Immune Response by Modulating the Tumor Microenvironment
L Wu, L Yang, X Qian, W Hu, S Wang… - Journal of Functional …, 2024 - mdpi.com
With the rapid development of tumor immunotherapy, nanoparticle vaccines have attracted
much attention as potential therapeutic strategies. A systematic review and analysis must be …
much attention as potential therapeutic strategies. A systematic review and analysis must be …
Hesperidin suppressed metastasis, angiogenesis and tumour growth in Balb/c mice model of breast cancer
E Shakiba, A Bazi, H Ghasemi… - Journal of Cellular …, 2023 - Wiley Online Library
Considering the unfavourable response of breast cancer (BC) to treatment, we assessed the
therapeutic potential hesperidin in mice bearing 4T1 BC tumours. Anti‐tumour effects were …
therapeutic potential hesperidin in mice bearing 4T1 BC tumours. Anti‐tumour effects were …
Inhibiting CXCR4 reduces immunosuppressive effects of myeloid cells in breast cancer immunotherapy
NG Ciavattone, A Bevoor, A Farfel, A Rehman… - Scientific Reports, 2025 - nature.com
Patients with triple negative breast cancer (TNBC) show only modest response rates to
immune checkpoint inhibitor immunotherapy, motivating ongoing efforts to identify …
immune checkpoint inhibitor immunotherapy, motivating ongoing efforts to identify …
Advancing cancer immunotherapy: from innovative preclinical models to clinical insights
The rapid expansion of cancer immunology and immunotherapy builds upon the success of
early immune checkpoint inhibitors (ICI) and chimeric antigen receptor T cells for some …
early immune checkpoint inhibitors (ICI) and chimeric antigen receptor T cells for some …
Patterns of immune evasion in triple-negative breast cancer and new potential therapeutic targets: a review
L Serrano García, B Jávega… - Frontiers in …, 2024 - frontiersin.org
Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer
characterized by the absence of progesterone and estrogen receptors and low (or absent) …
characterized by the absence of progesterone and estrogen receptors and low (or absent) …
An insight into the role of innate immune cells in breast tumor microenvironment
The immune background of breast cancer is highly heterogeneous and the immune system
of the human body plays a dual role by both promoting and suppressing its progression …
of the human body plays a dual role by both promoting and suppressing its progression …
Tumor Microenvironment Modulation and Its Impact on Immunotherapy in Triple-Negative Breast Cancer
Triple-negative breast cancer (TNBC) is known as a refractory and inoperable breast cancer
subtype with the worst prognosis. The poor treatment response due to the lack of specific …
subtype with the worst prognosis. The poor treatment response due to the lack of specific …