CRISPR-Cas13 in malaria parasite: Diagnosis and prospective gene function identification

E Quansah, Y Chen, S Yang, J Wang, D Sun… - Frontiers in …, 2023 - frontiersin.org
Malaria caused by Plasmodium is still a serious public health problem. Genomic editing is
essential to understand parasite biology, elucidate mechanical pathways, uncover gene …

Targeted testing and treatment to reduce human malaria transmission in high-risk populations: A systematic review

B Bhamani, EM Coma-Cros, M Tusell… - … American Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
As countries approach elimination of malaria, groups with increased exposure to malaria
vectors or poor access to health services may serve as important human reservoirs of …

Sensitive detection of asymptomatic and symptomatic malaria with seven novel parasite-specific LAMP assays and translation for use at point-of-care

K Malpartida-Cardenas, N Moser, F Ansah… - Microbiology …, 2023 - journals.asm.org
Human malaria is a life-threatening parasitic disease with high impact in the sub-Saharan
Africa region, where 95% of global cases occurred in 2021. While most malaria diagnostic …

[HTML][HTML] Performance Evaluation of Nested Polymerase Chain Reaction (Nested PCR), Light Microscopy, and Plasmodium falciparum Histidine-Rich Protein 2 Rapid …

OB Awosolu, ZS Yahaya, MT Farah Haziqah, TA Olusi - Pathogens, 2022 - mdpi.com
Malaria remains a major public health challenge worldwide. In order to ensure a prompt and
accurate malaria diagnosis, the World Health Organization recommended the confirmatory …

Low frequency of Plasmodium falciparum hrp2/3 deletions from symptomatic infections at a primary healthcare facility in Kilifi, Kenya

D Okanda, L Ndwiga, V Osoti, N Achieng… - Frontiers in …, 2023 - frontiersin.org
There is a growing concern for malaria control in the Horn of Africa region due to the spread
and rise in the frequency of Plasmodium falciparum Histidine-rich Protein (hrp) 2 and 3 …

[PDF][PDF] Seasonal Dynamics of Symptomatic and Asymptomatic Plasmodium falciparum and Plasmodium vivax Infections in Coendemic Low-Transmission Settings …

E Molla, S Dugassa, L Alemayehu… - The American Journal …, 2024 - researchgate.net
Ethiopia has a plan to eliminate malaria in selected low-transmission districts by 2025.
However, complex factors such as seasonality, focal heterogeneity, and coendemicity of …

[HTML][HTML] Exploring Biomarkers for Malaria: Advances in Early Detection and Asymptomatic Diagnosis

JA Harmonis, SAF Kusuma, Y Rukayadi, AN Hasanah - Biosensors, 2025 - mdpi.com
Malaria is a tropical disease caused by the Plasmodium parasite, which was responsible for
249 million cases worldwide in 2022. Malaria is currently diagnosed using RDTs, PCR …

Evaluating Malaria Rapid Diagnostic Tests and Microscopy for Detecting Plasmodium Infection and Status of Plasmodium falciparum Histidine-Rich Protein 2/3 Gene …

M Ikegbunam, M Maurer, H Abone… - The American Journal …, 2024 - europepmc.org
Delays in malaria diagnosis increase treatment failures and deaths. In endemic regions,
standard diagnostic methods are microscopy and malaria rapid diagnostic tests (mRDTs) …

[HTML][HTML] Multiplex reverse transcription polymerase chain reaction combined with a microwell hybridization assay screening for arbovirus and parasitic infections in …

P Calderon-Ruiz, G Haist, A Mascus… - Tropical Medicine and …, 2023 - mdpi.com
Acute febrile syndrome is a frequent reason for medical consultations in tropical and
subtropical countries where the cause could have an infectious origin. Malaria and dengue …

Multiple Plasmodium falciparum drug resistance polymorphisms identified in a pregnant woman with severe malaria and a concomitant spontaneous abortion in …

MA Oboh, F Faal, OE Adeniji, S Correa, AU Amawu… - Malaria journal, 2022 - Springer
Background The development of resistance by Plasmodium falciparum to anti-malarial
drugs impedes any benefits of the drug. In addition, absence or delayed availability of …